9d35: Difference between revisions
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==Proteasome core particle assembly intermediate 5-alpha/3-beta/Ump1 purified from Saccharomyces cerevisiae.== | |||
<StructureSection load='9d35' size='340' side='right'caption='[[9d35]], [[Resolution|resolution]] 3.26Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9d35]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9D35 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9D35 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.26Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9d35 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9d35 OCA], [https://pdbe.org/9d35 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9d35 RCSB], [https://www.ebi.ac.uk/pdbsum/9d35 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9d35 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PSA1_YEAST PSA1_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Chen X]] | |||
[[Category: Kaur M]] | |||
[[Category: Roelofs J]] | |||
[[Category: Walters KJ]] | |||
Latest revision as of 06:08, 20 August 2025
Proteasome core particle assembly intermediate 5-alpha/3-beta/Ump1 purified from Saccharomyces cerevisiae.
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