9ebh: Difference between revisions

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'''Unreleased structure'''


The entry 9ebh is ON HOLD  until Paper Publication
==Human adenosine A3 receptor Gi1 complex bound to adenosine==
 
<StructureSection load='9ebh' size='340' side='right'caption='[[9ebh]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
Authors: Zhang, L., Mobbs, J.I., Glukhova, A., Thal, D.M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9ebh]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EBH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EBH FirstGlance]. <br>
Description: Human adenosine A3 receptor Gi1 complex bound to adenosine
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADN:ADENOSINE'>ADN</scene></td></tr>
[[Category: Thal, D.M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ebh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ebh OCA], [https://pdbe.org/9ebh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ebh RCSB], [https://www.ebi.ac.uk/pdbsum/9ebh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ebh ProSAT]</span></td></tr>
[[Category: Mobbs, J.I]]
</table>
[[Category: Glukhova, A]]
== Function ==
[[Category: Zhang, L]]
[https://www.uniprot.org/uniprot/GNAI1_HUMAN GNAI1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(i) proteins are involved in hormonal regulation of adenylate cyclase: they inhibit the cyclase in response to beta-adrenergic stimuli. The inactive GDP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.<ref>PMID:17635935</ref> <ref>PMID:17264214</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Glukhova A]]
[[Category: Mobbs JI]]
[[Category: Thal DM]]
[[Category: Zhang L]]
Retrieved from "https://proteopedia.org/9ebh"