9ehs: Difference between revisions

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'''Unreleased structure'''


The entry 9ehs is ON HOLD  until Paper Publication
==Structure of a human adenosine A3 receptor complex bound to the covalent antagonist LUF7602==
 
<StructureSection load='9ehs' size='340' side='right'caption='[[9ehs]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
Authors: Zhang, L., Mobbs, J.I., Glukhova, A., Thal, D.M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9ehs]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EHS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EHS FirstGlance]. <br>
Description: Structure of a human adenosine A3 receptor complex bound to the covalent antagonist LUF7602
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1BII:4-({3-[(5S)-8-methoxy-2,4-dioxo-3-propyl-3,4-dihydropyrido[2,1-f]purin-1(2H)-yl]propyl}carbamoyl)benzene-1-sulfonyl+fluoride'>A1BII</scene></td></tr>
[[Category: Glukhova, A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ehs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ehs OCA], [https://pdbe.org/9ehs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ehs RCSB], [https://www.ebi.ac.uk/pdbsum/9ehs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ehs ProSAT]</span></td></tr>
[[Category: Zhang, L]]
</table>
[[Category: Thal, D.M]]
== Function ==
[[Category: Mobbs, J.I]]
[https://www.uniprot.org/uniprot/AA3R_HUMAN AA3R_HUMAN] Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase (PubMed:8234299).<ref>PMID:8234299</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Glukhova A]]
[[Category: Mobbs JI]]
[[Category: Thal DM]]
[[Category: Zhang L]]