9kyl: Difference between revisions
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==Crystal structure of human TRIP4 in complex with 11bp dsDNA== | |||
<StructureSection load='9kyl' size='340' side='right'caption='[[9kyl]], [[Resolution|resolution]] 2.15Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9kyl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KYL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KYL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kyl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kyl OCA], [https://pdbe.org/9kyl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kyl RCSB], [https://www.ebi.ac.uk/pdbsum/9kyl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kyl ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TRIP4_HUMAN TRIP4_HUMAN] Transcription coactivator of nuclear receptors which functions in conjunction with CBP-p300 and SRC-1 and may play an important role in establishing distinct coactivator complexes under different cellular conditions. Plays a pivotal role in the transactivation of NF-kappa-B, SRF and AP1. Acts as a mediator of transrepression between nuclear receptor and either AP1 or NF-kappa-B. Plays a role in androgen receptor transactivation and in testicular function (By similarity).<ref>PMID:12077347</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Guo WT]] | |||
[[Category: Meng CY]] | |||
[[Category: Wen Y]] | |||
[[Category: Wu BX]] | |||
Latest revision as of 06:19, 20 August 2025
Crystal structure of human TRIP4 in complex with 11bp dsDNA
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