9m5u: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9m5u is ~~ON HOLD until Paper Publication~~

==Cryo-EM structure of Arabidopsis thaliana MET1 (aa:621-1534) in complex with hemimethylated DNA analog==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9m5u]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9M5U OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9M5U FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.74Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene>, <scene name='pdbligand=A1L82:[(2~{R},3~{S},5~{R})-5-[(2~{R},4~{R},5~{S})-4-azanyl-5-fluoranyl-5-methyl-2-oxidanyl-1,3-diazinan-1-yl]-3-oxidanyl-oxolan-2-yl]methyl+dihydrogen+phosphate'>A1L82</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9m5u OCA], [https://pdbe.org/9m5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9m5u RCSB], [https://www.ebi.ac.uk/pdbsum/9m5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9m5u ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/DNMT1_ARATH DNMT1_ARATH] Maintains chromatin CpG methylation that plays a role in genomic imprinting, regulation of embryogenesis and seed viability. Required for proper patterns of CG DNA methylation in dividing cells. Required for MEA promoter methylation in seeds.<ref>PMID:12456661</ref> <ref>PMID:12663548</ref> <ref>PMID:12669067</ref> <ref>PMID:14667411</ref> <ref>PMID:16531498</ref> <ref>PMID:17012404</ref> <ref>PMID:18820427</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Arabidopsis thaliana]]

[[Category: Large Structures]]

[[Category: Synthetic construct]]

[[Category: Arita K]]

[[Category: Kikuchi A]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9m5u is ON HOLD  until Paper Publication
+==Cryo-EM structure of Arabidopsis thaliana MET1 (aa:621-1534) in complex with hemimethylated DNA analog==
+<StructureSection load='9m5u' size='340' side='right'caption='[[9m5u]], [[Resolution|resolution]] 2.74&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9m5u]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9M5U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9M5U FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.74&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene>, <scene name='pdbligand=A1L82:[(2~{R},3~{S},5~{R})-5-[(2~{R},4~{R},5~{S})-4-azanyl-5-fluoranyl-5-methyl-2-oxidanyl-1,3-diazinan-1-yl]-3-oxidanyl-oxolan-2-yl]methyl+dihydrogen+phosphate'>A1L82</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9m5u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9m5u OCA], [https://pdbe.org/9m5u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9m5u RCSB], [https://www.ebi.ac.uk/pdbsum/9m5u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9m5u ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/DNMT1_ARATH DNMT1_ARATH] Maintains chromatin CpG methylation that plays a role in genomic imprinting, regulation of embryogenesis and seed viability. Required for proper patterns of CG DNA methylation in dividing cells. Required for MEA promoter methylation in seeds.<ref>PMID:12456661</ref> <ref>PMID:12663548</ref> <ref>PMID:12669067</ref> <ref>PMID:14667411</ref> <ref>PMID:16531498</ref> <ref>PMID:17012404</ref> <ref>PMID:18820427</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Arabidopsis thaliana]]
+[[Category: Large Structures]]
+[[Category: Synthetic construct]]
+[[Category: Arita K]]
+[[Category: Kikuchi A]]