9n6i: Difference between revisions
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==2.61 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 2:1 complex== | |||
<StructureSection load='9n6i' size='340' side='right'caption='[[9n6i]], [[Resolution|resolution]] 2.61Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9n6i]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9N6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9N6I FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.61Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9n6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9n6i OCA], [https://pdbe.org/9n6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9n6i RCSB], [https://www.ebi.ac.uk/pdbsum/9n6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9n6i ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Xenopus laevis]] | |||
[[Category: Armache J-P]] | |||
[[Category: Bowman GD]] | |||
[[Category: Folkwein HJ]] | |||
[[Category: Nodelman IM]] | |||
Latest revision as of 06:34, 20 August 2025
2.61 A S.cerevisiae Chd1[L886G/L889G/L891G]-nucleosome 2:1 complex
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