9hg2: Difference between revisions
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==Crystal structure of M. smegmatis GMP reductase in complex with IMP and ATP.== | |||
<StructureSection load='9hg2' size='340' side='right'caption='[[9hg2]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9hg2]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis Mycolicibacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HG2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=IMP:INOSINIC+ACID'>IMP</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hg2 OCA], [https://pdbe.org/9hg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hg2 RCSB], [https://www.ebi.ac.uk/pdbsum/9hg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hg2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/GUAB1_MYCS2 GUAB1_MYCS2] Involved in the purine-salvage pathway (PubMed:35338694). Catalyzes the NADPH-dependent conversion of GMP to IMP (PubMed:35338694). Is not essential for viability, but may contribute to the regulation of the purine nucleotide pool by recycling GMP to IMP (PubMed:35338694).<ref>PMID:35338694</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycolicibacterium smegmatis]] | |||
[[Category: Dolezal M]] | |||
[[Category: Pichova I]] | |||
Latest revision as of 07:13, 27 August 2025
Crystal structure of M. smegmatis GMP reductase in complex with IMP and ATP.
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