Histone deacetylase: Difference between revisions
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* '''HDAC class IIa''' lack enzymatic activity<ref>PMID:25244360</ref>. <br /> | * '''HDAC class IIa''' lack enzymatic activity<ref>PMID:25244360</ref>. <br /> | ||
* '''HDAC class III''' called '''sirtuin''' - (Silent Information Regulator) (SIRT) are NAD-dependent HDAC. This protein is bifunctional and can act as a deacylase or as mono-ADP-acetyltransferase. <ref>PMID:18249170</ref>.<br /> | * '''HDAC class III''' called '''sirtuin''' - (Silent Information Regulator) (SIRT) are NAD-dependent HDAC. This protein is bifunctional and can act as a deacylase or as mono-ADP-acetyltransferase. <ref>PMID:18249170</ref>.<br /> | ||
* '''HDAC Rpd3''' belongs to class I and is involved in transcriptional repression <ref>PMID:9512514</ref>.<br /> | |||
For HDAC8 see - [[Histone deacetylase 8 (HDAC8)]].<br /> | For HDAC8 see - [[Histone deacetylase 8 (HDAC8)]].<br /> | ||
