9ntc: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9ntc is ~~ON HOLD~~

==Structure of Synaptic Vesicle Protein 2A Bound to Brivaracetam and UCB1244283==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9ntc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NTC OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9NTC FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.05Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1B1I:(3~{S})-4-(3,5-dimethylphenyl)-~{N}-(2-methoxyphenyl)-3-methyl-butanamide'>A1B1I</scene>, <scene name='pdbligand=A1B1J:(3~{R})-4-(3,5-dimethylphenyl)-~{N}-(2-methoxyphenyl)-3-methyl-butanamide'>A1B1J</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=VLX:(2~{S})-2-[(4~{R})-2-oxidanylidene-4-propyl-pyrrolidin-1-yl]butanamide'>VLX</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9ntc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ntc OCA], [https://pdbe.org/9ntc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ntc RCSB], [https://www.ebi.ac.uk/pdbsum/9ntc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ntc ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/SV2A_HUMAN SV2A_HUMAN] Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Coleman JA]]

[[Category: Horanyi PS]]

[[Category: Ledecq M]]

[[Category: Martin MF]]

[[Category: Mittal A]]

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-'''Unreleased structure'''
-The entry 9ntc is ON HOLD
+==Structure of Synaptic Vesicle Protein 2A Bound to Brivaracetam and UCB1244283==
+<StructureSection load='9ntc' size='340' side='right'caption='[[9ntc]], [[Resolution|resolution]] 3.05&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9ntc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9NTC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9NTC FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.05&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1B1I:(3~{S})-4-(3,5-dimethylphenyl)-~{N}-(2-methoxyphenyl)-3-methyl-butanamide'>A1B1I</scene>, <scene name='pdbligand=A1B1J:(3~{R})-4-(3,5-dimethylphenyl)-~{N}-(2-methoxyphenyl)-3-methyl-butanamide'>A1B1J</scene>, <scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=VLX:(2~{S})-2-[(4~{R})-2-oxidanylidene-4-propyl-pyrrolidin-1-yl]butanamide'>VLX</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ntc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ntc OCA], [https://pdbe.org/9ntc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ntc RCSB], [https://www.ebi.ac.uk/pdbsum/9ntc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ntc ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/SV2A_HUMAN SV2A_HUMAN] Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Coleman JA]]
+[[Category: Horanyi PS]]
+[[Category: Ledecq M]]
+[[Category: Martin MF]]
+[[Category: Mittal A]]