9ui4: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 9ui4 is ~~ON HOLD until Paper Publication~~

==Rad51 presynaptic complex==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9ui4]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UI4 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9UI4 FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.91Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9ui4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ui4 OCA], [https://pdbe.org/9ui4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ui4 RCSB], [https://www.ebi.ac.uk/pdbsum/9ui4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ui4 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/RAD51_MOUSE RAD51_MOUSE] Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR) (PubMed:15834424). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. Also involved in interstrand cross-link repair (By similarity).[UniProtKB:Q06609]<ref>PMID:15834424</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Mus musculus]]

[[Category: Ho MC]]

[[Category: Luo SC]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9ui4 is ON HOLD  until Paper Publication
+==Rad51 presynaptic complex==
+<StructureSection load='9ui4' size='340' side='right'caption='[[9ui4]], [[Resolution|resolution]] 2.91&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9ui4]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9UI4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9UI4 FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.91&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ANP:PHOSPHOAMINOPHOSPHONIC+ACID-ADENYLATE+ESTER'>ANP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ui4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ui4 OCA], [https://pdbe.org/9ui4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ui4 RCSB], [https://www.ebi.ac.uk/pdbsum/9ui4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ui4 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/RAD51_MOUSE RAD51_MOUSE] Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR) (PubMed:15834424). Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Recruited to resolve stalled replication forks during replication stress. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. Also involved in interstrand cross-link repair (By similarity).[UniProtKB:Q06609]<ref>PMID:15834424</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Mus musculus]]
+[[Category: Ho MC]]
+[[Category: Luo SC]]