9qky: Difference between revisions
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The | ==The structure of the DNA-binding domain of Nuclear Factor 1 X bound to NFI consensus DNA sequence== | ||
<StructureSection load='9qky' size='340' side='right'caption='[[9qky]], [[Resolution|resolution]] 3.86Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9qky]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QKY FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.86Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qky OCA], [https://pdbe.org/9qky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qky RCSB], [https://www.ebi.ac.uk/pdbsum/9qky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qky ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[Category: Gourlay | [https://www.uniprot.org/uniprot/NFIX_MOUSE NFIX_MOUSE] Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. Isoform NFIX1 acts as a transcriptional activator while isoform NFIX3 acts as a repressor.<ref>PMID:8581067</ref> | ||
[[Category: Tiberi | == References == | ||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Bonnet DMV]] | |||
[[Category: Chaves-Sanjuan A]] | |||
[[Category: Gourlay LJ]] | |||
[[Category: Nardini M]] | |||
[[Category: Tiberi M]] | |||
Latest revision as of 05:42, 17 September 2025
The structure of the DNA-binding domain of Nuclear Factor 1 X bound to NFI consensus DNA sequence
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