7vdv: Difference between revisions
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==== | ==The overall structure of human chromatin remodeling PBAF-nucleosome complex== | ||
<StructureSection load='7vdv' size='340' side='right'caption='[[7vdv]]' scene=''> | <StructureSection load='7vdv' size='340' side='right'caption='[[7vdv]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7vdv]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VDV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VDV FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vdv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vdv OCA], [https://pdbe.org/7vdv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vdv RCSB], [https://www.ebi.ac.uk/pdbsum/7vdv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vdv ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.4Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vdv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vdv OCA], [https://pdbe.org/7vdv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vdv RCSB], [https://www.ebi.ac.uk/pdbsum/7vdv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vdv ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | |||
==See Also== | |||
*[[Actin-related protein 3D structures|Actin-related protein 3D structures]] | |||
*[[Histone 3D structures|Histone 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Synthetic construct]] | ||
[[Category: Xenopus laevis]] | |||
[[Category: Chen KJ]] | |||
[[Category: Chen ZC]] | |||
[[Category: Yuan JJ]] | |||
Latest revision as of 05:56, 17 September 2025
The overall structure of human chromatin remodeling PBAF-nucleosome complex
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