9do6: Difference between revisions
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==Membrane-spanning OlyA/PlyB pore complex focused refinement== | |||
<StructureSection load='9do6' size='340' side='right'caption='[[9do6]], [[Resolution|resolution]] 2.54Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9do6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pleurotus_ostreatus Pleurotus ostreatus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9DO6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9DO6 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.54Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9do6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9do6 OCA], [https://pdbe.org/9do6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9do6 RCSB], [https://www.ebi.ac.uk/pdbsum/9do6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9do6 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/OLYA6_PLEOS OLYA6_PLEOS] Has hemolytic activity against bovine erythrocytes at nanomolar concentrations in vitro. Promotes active pleurotolysin B (PlyB)-dependent permeabilization of membranes rich in cholesterol and sphingomyelin. May play an important role in the initial phase of fungal fruiting.<ref>PMID:12020804</ref> <ref>PMID:23806422</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Pleurotus ostreatus]] | |||
[[Category: Chen Z]] | |||
[[Category: Han Y]] | |||
[[Category: Li Y]] | |||
[[Category: Radhakrishnan A]] | |||
[[Category: Smothers J]] | |||
Latest revision as of 05:35, 24 September 2025
Membrane-spanning OlyA/PlyB pore complex focused refinement
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