9qrl: Difference between revisions
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==DNA polymerase with inhibitor #2== | |||
<StructureSection load='9qrl' size='340' side='right'caption='[[9qrl]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9qrl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecium Enterococcus faecium] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QRL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QRL FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1I9T:2-[(3,4-dichlorophenyl)methylamino]-7-(2-morpholin-4-ylethyl)-1~{H}-purin-6-one'>A1I9T</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qrl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qrl OCA], [https://pdbe.org/9qrl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qrl RCSB], [https://www.ebi.ac.uk/pdbsum/9qrl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qrl ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[https://www.uniprot.org/uniprot/A0A9X4B319_ENTFC A0A9X4B319_ENTFC] DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The alpha chain is the DNA polymerase.[ARBA:ARBA00025611] Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.[ARBA:ARBA00003452][HAMAP-Rule:MF_00356] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Enterococcus faecium]] | |||
[[Category: Escherichia coli]] | |||
[[Category: Large Structures]] | |||
[[Category: Lamers MH]] | |||
[[Category: Smits WK]] | |||
[[Category: Urem M]] | |||
