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'''Unreleased structure'''


The entry 9si9 is ON HOLD
==Chromosomal Passenger Complex in complex with H3T3ph Nucleosome (Class0)==
 
<StructureSection load='9si9' size='340' side='right'caption='[[9si9]], [[Resolution|resolution]] 2.86&Aring;' scene=''>
Authors: Gireesh, A., Abad, M.A., Sotelo-Parrilla, P., Jeyaprakash, A.A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9si9]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9SI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9SI9 FirstGlance]. <br>
Description: Chromosomal Passenger Complex in complex with H3T3ph Nucleosome (Class0)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.86&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
[[Category: Jeyaprakash, A.A]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9si9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9si9 OCA], [https://pdbe.org/9si9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9si9 RCSB], [https://www.ebi.ac.uk/pdbsum/9si9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9si9 ProSAT]</span></td></tr>
[[Category: Gireesh, A]]
</table>
[[Category: Sotelo-Parrilla, P]]
== Function ==
[[Category: Abad, M.A]]
[https://www.uniprot.org/uniprot/H32_XENLA H32_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Xenopus laevis]]
[[Category: Abad MA]]
[[Category: Gireesh A]]
[[Category: Jeyaprakash AA]]
[[Category: Sotelo-Parrilla P]]
Retrieved from "https://proteopedia.org/9si9"