9wvi: Difference between revisions
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==Crystal structure of TONSL UBL mutant - R934W== | |||
<StructureSection load='9wvi' size='340' side='right'caption='[[9wvi]], [[Resolution|resolution]] 2.19Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9wvi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WVI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WVI FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wvi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wvi OCA], [https://pdbe.org/9wvi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wvi RCSB], [https://www.ebi.ac.uk/pdbsum/9wvi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wvi ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Karmakar | == Function == | ||
[https://www.uniprot.org/uniprot/TONSL_HUMAN TONSL_HUMAN] Component of the MMS22L-TONSL complex, a complex that stimulates the recombination-dependent repair of stalled or collapsed replication forks. The MMS22L-TONSL complex is required to maintain genome integrity during DNA replication by promoting homologous recombination-mediated repair of replication fork-associated double-strand breaks. It may act by mediating the assembly of RAD51 filaments on ssDNA. Within the complex, may act as a scaffold.<ref>PMID:21055983</ref> <ref>PMID:21055984</ref> <ref>PMID:21055985</ref> <ref>PMID:7738005</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Karmakar A]] | |||
[[Category: Roy S]] | |||