9e79: Difference between revisions
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==Crystal structure of the MIR domain of the S. cerevisiae mannosyltransferase Pmt4== | |||
<StructureSection load='9e79' size='340' side='right'caption='[[9e79]], [[Resolution|resolution]] 1.64Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9e79]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9E79 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9E79 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9e79 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9e79 OCA], [https://pdbe.org/9e79 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9e79 RCSB], [https://www.ebi.ac.uk/pdbsum/9e79 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9e79 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Li | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/PMT4_YEAST PMT4_YEAST] Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a homodimeric complex to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins. Specifically acts on secretory proteins with an ER-luminally oriented Ser/Thr-rich region flanked by a membrane anchor such as FUS1, AXL2, GAS1, KEX2, MID2, WSC1, WSC2, OPY2, PRM5, RAX2, or YNL176.<ref>PMID:10366591</ref> <ref>PMID:14673142</ref> <ref>PMID:17470820</ref> <ref>PMID:9184828</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Du M]] | |||
[[Category: Li H]] | |||
[[Category: Yuan Z]] | |||