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'''Unreleased structure'''


The entry 9i9i is ON HOLD  until Paper Publication
==Cryo-EM structure of CAK-CDK11==
 
<StructureSection load='9i9i' size='340' side='right'caption='[[9i9i]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
Authors: Cushing, V.I., Greber, B.J., McGeoch, A.J.S., Feng, J.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9i9i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9I9I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9I9I FirstGlance]. <br>
Description: Cryo-EM structure of CAK-CDK11
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
[[Category: Mcgeoch, A.J.S]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9i9i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9i9i OCA], [https://pdbe.org/9i9i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9i9i RCSB], [https://www.ebi.ac.uk/pdbsum/9i9i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9i9i ProSAT]</span></td></tr>
[[Category: Cushing, V.I]]
</table>
[[Category: Feng, J]]
== Function ==
[[Category: Greber, B.J]]
[https://www.uniprot.org/uniprot/CD11B_HUMAN CD11B_HUMAN] Plays multiple roles in cell cycle progression, cytokinesis and apoptosis. Involved in pre-mRNA splicing in a kinase activity-dependent manner. Isoform 7 may act as a negative regulator of normal cell cycle progression.<ref>PMID:12501247</ref> <ref>PMID:12624090</ref> <ref>PMID:18216018</ref> <ref>PMID:2217177</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Cushing VI]]
[[Category: Feng J]]
[[Category: Greber BJ]]
[[Category: McGeoch AJS]]
Retrieved from "https://proteopedia.org/9i9i"