9jui: Difference between revisions

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'''Unreleased structure'''


The entry 9jui is ON HOLD  until 2027-03-31
==Crystal structure of FFAT motif of Nir2 bound to VAPB==
 
<StructureSection load='9jui' size='340' side='right'caption='[[9jui]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9jui]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JUI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JUI FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jui OCA], [https://pdbe.org/9jui PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jui RCSB], [https://www.ebi.ac.uk/pdbsum/9jui PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jui ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/VAPB_MOUSE VAPB_MOUSE] Endoplasmic reticulum (ER)-anchored protein that mediates the formation of contact sites between the ER and endosomes via interaction with FFAT motif-containing proteins such as STARD3 or WDR44. Interacts with STARD3 in a FFAT motif phosphorylation dependent manner. Via interaction with WDR44 participates in neosynthesized protein export. Participates in the endoplasmic reticulum unfolded protein response (UPR) by inducing ERN1/IRE1 activity. Involved in cellular calcium homeostasis regulation.[UniProtKB:O95292]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Kim D]]
[[Category: Lee C]]
Retrieved from "https://proteopedia.org/9jui"