9yi3: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "9yi3" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of PprA S-F filament from Deinococcus radiodurans== | |||
<StructureSection load='9yi3' size='340' side='right'caption='[[9yi3]], [[Resolution|resolution]] 1.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9yi3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9YI3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.82Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> | ||
[[Category: Junop | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9yi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9yi3 OCA], [https://pdbe.org/9yi3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9yi3 RCSB], [https://www.ebi.ac.uk/pdbsum/9yi3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9yi3 ProSAT]</span></td></tr> | ||
[[Category: Szabla | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PPRA_DEIRA PPRA_DEIRA] dsDNA-binding protein that contributes to the ionizing radiation resistance of D.radiodurans. Plays a role in DNA repair and genome reconstitution, and is necessary for recovery from severe genomic fragmentation as a result of exposure to severe levels of ionizing radiation. In vitro, binds to double-stranded DNA carrying strand breaks and stimulates the DNA end-joining reaction catalyzed by DNA ligases. Thus, PprA plays a critical role in a non-homologous end-joining (NHEJ) pathway for the repair of radiation-induced DNA double-strands breaks. Cannot bind to dsDNA without strand breaks or single-stranded DNA.<ref>PMID:15454524</ref> <ref>PMID:15458422</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Deinococcus radiodurans]] | |||
[[Category: Large Structures]] | |||
[[Category: Junop MS]] | |||
[[Category: Szabla R]] | |||
Latest revision as of 07:21, 15 October 2025
Crystal structure of PprA S-F filament from Deinococcus radiodurans
| ||||||||||||
