Kinesin 3D Structures: Difference between revisions

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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
*KIF1 heavy chain
**[[5lt0]], [[5lt1]], [[5lt2]], [[5lt3]], [[5lt4]], [[9l6k]], [[9l78]] – hKHC (mutant) - human<br />
**[[7rik]] – hKHC - NMR<br />
**[[1mkj, [[5lt0]]]] – hKHC + ADP<br />
**[[9l7e]] – hKHC (mutant) + ADP<br />
**[[1bg2]] – hKHC MD <br />
**[[3j8x]], [[3j8y]] – hKHC MD + GTP + GDP + tubulin<br />
**[[6ojq]] – hKHC MD + Tubulin + G2P + GTP – Cryo EM<br />
**[[4lnu]] – hKHC + Tubulin + designed ankyrin repeat
**[[4hna]] – hKHC + Tubulin + designed ankyrin repeat protein + Mg-ADP + GDP + GTP + AlF4<br />
**[[9l7m]] – hKHC MD + GTP + tubulin – Cryo EM<br />
**[[8ixb]], [[8ixd]], [[8ixe]] – hKHC MD + Tubulin + GMPCPP – Cryo EM<br />
**[[8rhb]], [[8rhh]] – hKHC + Tubulin + AMPPNP – Cryo EM<br />
**[[8rik]], [[8riz]], [[9gnq]] – hKHC + Tubulin + ADP + GDP + GTP – Cryo EM<br />
**[[6ign]], [[6igv]] – mKHC coiled coil domain 444-566  <br />
**[[4atx]] - rKHC MD+ Tubulin  – rat - Cryo EM<br />


*KIF1A, KIF1B, KIF1C or kinesin-3  
*KIF1A, KIF1B, KIF1C or kinesin-3  


**[[1bg2]] – hKIF MD - human<br />
**[[4hna]], [[4lnu]] – hKIF1 + Tubulin + designed ankyrin repeat protein + Mg-ADP + GDP + GTP + AlF4<br />
**[[4uxy]] – hKIF1 MD + Tubulin + GDP + GTP – Cryo EM<br />
**[[4uxy]] – hKIF1 MD + Tubulin + GDP + GTP – Cryo EM<br />
**[[6ojq]] – hKIF1 MD + Tubulin + G2P + GTP – Cryo EM<br />
**[[4uy0]] – hKIF1 MD + Tubulin + GDP + GTP + ADP – Cryo EM<br />
**[[4uy0]] – hKIF1 MD + Tubulin + GDP + GTP + ADP – Cryo EM<br />
**[[4uxo]], [[4uxp]], [[4uxr]], [[4uxs]], [[4uxt]] - hKIF + tubulin 1B, 2B chains + GDP + GTP – Cryo EM <br />
**[[4uxo]], [[4uxp]], [[4uxr]], [[4uxs]], [[4uxt]] - hKIF + tubulin 1B, 2B chains + GDP + GTP – Cryo EM <br />
**[[2p4n]] – hKIF+ Tubulin  – EM docking<br />
**[[2p4n]] – hKIF+ Tubulin  – EM docking<br />
**[[1mkj]] – hKIF MD+docked FNL<br />
**[[6zph]] – hKIF MD + KIF-binding protein – Cryo EM<br />
**[[6zph]] – hKIF MD + KIF-binding protein – Cryo EM<br />
**[[9ko8]] – hKIF1C 714-809 + Hook3 553-624 <br />
**[[2wbe]] – bKIF MD+FNL+Tubulin +AMPPNP – bovine <br />
**[[2wbe]] – bKIF MD+FNL+Tubulin +AMPPNP – bovine <br />
**[[3edl]] – bKIF MD+ Tubulin – EM<br />
**[[3edl]] – bKIF MD+ Tubulin – EM<br />
**[[4atx]] - rKIF MD+ Tubulin  – rat - Cryo EM<br />
**[[8tt7]] - rKIF neck 325-376 - NMR<br />


*KIF-like 1A, KIF-like 1B, KIF-like 1C
*KIF-like 1A, KIF-like 1B, KIF-like 1C


**[[4ejq]], [[4egx]] – hKIFL 1A CC1-FHA domain 430-607<br />
**[[4ejq]], [[4egx]] – hKIFL 1A CC1-FHA domain 430-607<br />
**[[5lt0]], [[5lt1]], [[5lt2]], [[5lt3]], [[5lt4]] – hKIFL 1 MD (mutant) <br />
**[[8uts]] – hKIFL 1A MD + tubulin – Cryo EM <br />
**[[8utn]], [[8uto]], [[8utp]], [[8utq]], [[8uty]] – hKIFL 1A MD + tubulin + ANP + GDP + GTP – Cryo EM <br />
**[[8utr]] – hKIFL 1A MD + tubulin + ADP – Cryo EM <br />
**[[8utv]] – hKIFL 1A MD (mutant) + tubulin + ADP – Cryo EM <br />
**[[8utt]], [[8utu]], [[8utw]] – hKIFL 1A MD (mutant) + tubulin + ANP + GDP + GTP – Cryo EM <br />
**[[2g1l]] – hKIFL 1C FHA domain<br />
**[[2g1l]] – hKIFL 1C FHA domain<br />
**[[5wdh]] – hKIFL 1C MD<br />
**[[5wdh]] – hKIFL 1C MD<br />
**[[2rep]] – hKIFL 1C MD<br />
**[[2eh0]] – hKIFL 1B FHA domain – NMR<br />
**[[2eh0]] – hKIFL 1B FHA domain – NMR<br />
**[[2hxh]] – pKIFL 1A head+ADP - pig<br />
**[[2hxh]] – pKIFL 1A head+ADP - pig<br />
Line 42: Line 62:
**[[2gry]] – hKIFL 2+ADP<br />
**[[2gry]] – hKIFL 2+ADP<br />
**[[6bbn]] – hKIFL 2A MD + Tubulin + Darpin<br />
**[[6bbn]] – hKIFL 2A MD + Tubulin + Darpin<br />
**[[9j20]], [[9jwv]] – hKIFL 2A MD + WDR5<br />
**[[5mio]] – hKIFL 2C MD + Tubulin <br />
**[[5mio]] – hKIFL 2C MD + Tubulin <br />
**[[1v8j]], [[5xja]], [[5xjb]] – mKIFL 2C MD+Mg-ADP<br />
**[[1v8j]], [[5xja]], [[5xjb]] – mKIFL 2C MD+Mg-ADP<br />
Line 48: Line 69:
**[[1v8k]] – mKIFL 2C MD+Mg-AMPPNP<br />
**[[1v8k]] – mKIFL 2C MD+Mg-AMPPNP<br />
**[[2vvg]] – KIF2 MD – ''Giardia intestinalis''<br />
**[[2vvg]] – KIF2 MD – ''Giardia intestinalis''<br />
*KIF-like 3A, KIF-like 3B
**[[9w9i]] – hKIFL 3A + hKIFL 3B + KAP3 + mAPC – Cryo EM<br />
**[[9w9h]] – hKIFL 3A + hKIFL 3B + KAP3 – Cryo EM<br />


*KIF-like 3B, KIF-like 3C or kinesin-2
*KIF-like 3B, KIF-like 3C or kinesin-2


**[[3b6u]], [[3b6v]] – hKIFL 3B MD<br />
**[[3b6u]], [[3b6v]] – hKIFL 3B MD<br />
**[[5wde]] – hKIFL 3C+ADP<br />
**[[2h58]], [[5wde]] – hKIFL 3C+ADP<br />


*KIF4A, KIF4B or kinesin-4
*KIF4A, KIF4B or kinesin-4
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*KIF5B, KIF5C or kinesin-1
*KIF5B, KIF5C or kinesin-1


**[[6ign]], [[6igv]] – mKIF5B coiled coil domain 444-566  <br />
**[[3wrd]] – mKIF5C<br />
**[[3wrd]] – mKIF5C<br />
**[[3x2t]] – mKIF5C + ADP<br />
**[[3x2t]] – mKIF5C + ADP<br />
**[[3j6h]] – mKIF5C MD+Mg-GTP + G2P + tubulin <br />
**[[3j6h]] – mKIF5C MD+Mg-GTP + G2P + tubulin <br />
**[[3j8x]], [[3j8y]] – mKIF5C MD+ GTP + GDP + tubulin<br />
**[[3j8x]], [[3j8y]] – hKIF5C MD+ GTP + GDP + tubulin<br />
**[[2y5w]], [[2y65]] - DmKIF MD – Drosophila melanogasgter<br />
**[[2y5w]], [[2y65]] - DmKIF MD – Drosophila melanogasgter<br />
**[[4pxt]], [[4pxu]] – DmKIF MD (mutant)<br />
**[[4pxt]], [[4pxu]] – DmKIF MD (mutant)<br />
**[[1n6m]] – DmKIF MD+FNL<br />
**[[1n6m]] – DmKIF MD+FNL<br />
**[[3l1c]] – DmNCD (mutant)<br />
**[[3l1c]] – DmNCD (mutant)<br />
*KIF-like 6
**[[7wrg]] - CeKIFL - Caenorhabditis elegans<br />


*KIF-like 7 or kinesin-4
*KIF-like 7 or kinesin-4
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**[[6mlq]] – hKIFL 7 MD + Tubulin + GTP + GDP + ADP – Cryo EM<br />
**[[6mlq]] – hKIFL 7 MD + Tubulin + GTP + GDP + ADP – Cryo EM<br />
**[[7rx0]] – hKIFL 7 MD + GLI2 ANTubulin + GTP + GDP + G2P – Cryo EM<br />
**[[7rx0]] – hKIFL 7 MD + GLI2 ANTubulin + GTP + GDP + G2P – Cryo EM<br />
*KIF8B
**[[7z2a]], [[7z2b]], [[7z2c]] – KIF8B + pTUBA+pTUBB +G2P + GTP – Plasmodium berghei – Cryo EM <br />
*KIF-like 8
**[[9crw]] – hKIFL 8 474-705 <br />


*KIF-like 9 or kinesin-9
*KIF-like 9 or kinesin-9
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**[[4bxn]], [[4as7]] – hKIFL 11+inhibitor +ADP + Cd<br />
**[[4bxn]], [[4as7]] – hKIFL 11+inhibitor +ADP + Cd<br />
**[[3l9h]] – hKIFL 11+inhibitor +ADP <br />
**[[3l9h]] – hKIFL 11+inhibitor +ADP <br />
**[[4zhi]] – hKIFL 11 MD +ADP<br />
**[[4zhi]], [[8yhh]] – hKIFL 11 MD +ADP<br />
**[[1x88]], [[1q0b]] – hKIFL 11 +Mg + ADP+monastrol <br />
**[[1x88]], [[1q0b]] – hKIFL 11 +Mg + ADP+monastrol <br />
**[[4ap0]], [[4a5y]] – hKIFL 11 +MgADP + ispinesib + Mg<br />
**[[4ap0]], [[4a5y]] – hKIFL 11 +MgADP + ispinesib + Mg<br />
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**[[5m5i]], [[5m5l]], [[5m5m]], [[5m5n]], [[5m5o]] – fyKIFL Cut7 MD + tubulin + GDP + GTP + ANP + taxol – fission yeast – Cryo EM<br />
**[[5m5i]], [[5m5l]], [[5m5m]], [[5m5n]], [[5m5o]] – fyKIFL Cut7 MD + tubulin + GDP + GTP + ANP + taxol – fission yeast – Cryo EM<br />
**[[6s8m]] – fyKIFL Cut7 MD + tubulin + GDP + GTP + ANP – Cryo EM<br />
**[[6s8m]] – fyKIFL Cut7 MD + tubulin + GDP + GTP + ANP – Cryo EM<br />
**[[9ikb]] – CeKIFL 11 + CeKIFL 20 + KAP <br />


*KIF11
*KIF11
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**[[7nb8]] – PfKIF MD + tubulin + GTP + G2P – ''Plasmodium falciparum'' – Cryo EM<br />
**[[7nb8]] – PfKIF MD + tubulin + GTP + G2P – ''Plasmodium falciparum'' – Cryo EM<br />
**[[7nba]] – PfKIF MD + tubulin + GTP + G2P + ANP – Cryo EM<br />
**[[7nba]] – PfKIF MD + tubulin + GTP + G2P + ANP – Cryo EM<br />
* KIF-like 12
**[[7x4n]] – CeKIFL 12 MD + tubulin + darpin + GDP + GTP + ANP – Cryo EM<br />


*KIF13A, KIF13B or kinesin-3
*KIF13A, KIF13B or kinesin-3
Line 134: Line 176:
**[[5djo]] – mKIFL 13A CC1-FHA domain <br />
**[[5djo]] – mKIFL 13A CC1-FHA domain <br />
**[[5djn]] – mKIFL 13A coiled-coil domain (mutant)<br />
**[[5djn]] – mKIFL 13A coiled-coil domain (mutant)<br />
*KIF14
**[[8yue]] – DmKIF14 + Tubulin + ADP – Cryo EM<br />
**[[8yy2]], [[8yy3]], [[8yy4]], [[8yy5]] – DmKIF14 (mutant) + Tubulin + GTP + GDP + ADP – Cryo EM<br />


*KIF-like 14 or kinesin-3
*KIF-like 14 or kinesin-3
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**[[5oam]] – hKIFL 18A MD + tubulin + GTP<br />
**[[5oam]] – hKIFL 18A MD + tubulin + GTP<br />
**[[5ocu]] – hKIFL 18A MD + tubulin + GTP + GDP + ANP<br />
**[[5ocu]] – hKIFL 18A MD + tubulin + GTP + GDP + ANP<br />
**[[9di0]] – hKIFL 18A MD + tubulin + GTP + GDP + ATP – Cryo EM<br />
**[[5ogc]] – hKIFL 18A MD + tubulin + GTP + GDP + taxol<br />
**[[5ogc]] – hKIFL 18A MD + tubulin + GTP + GDP + taxol<br />
**[[7rsi]] – hKIFL 18A MD + KIF-binding protein + ADP – Cryo EM<br />
**[[7rsi]] – hKIFL 18A MD + KIF-binding protein + ADP – Cryo EM<br />
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**[[6yip]] – hKIFL 20A coiled coil domain 596-668  <br />
**[[6yip]] – hKIFL 20A coiled coil domain 596-668  <br />
**[[8bjs]] – mKIFL 20A 55-510<br />
**[[5nd3]] – mKIFL 20A MD + tubulin <br />
**[[5nd3]] – mKIFL 20A MD + tubulin <br />
**[[5nd2]], [[5nd4]] – mKIFL 20A MD + tubulin + ADP <br />
**[[5nd2]], [[5nd4]] – mKIFL 20A MD + tubulin + ADP <br />
**[[5nd7]] – mKIFL 20A MD + tubulin + AMPPNP <br />
**[[5nd7]] – mKIFL 20A MD + tubulin + AMPPNP <br />
**[[8f18]], [[8f1a]] – mKIFL 20A MD + tubulin + GDP + GTP <br />
**[[5lef]] – mKIFL 20A residues 603-665 + RAB-6 <br />
**[[5lef]] – mKIFL 20A residues 603-665 + RAB-6 <br />
**[[5x3e]] - KIFL MD - Caenorhabditis elegans<br />
**[[5x3e]] - CeKIFL MD <br />


*KIF-like 21A or kinesin-4
*KIF-like 21A or kinesin-4
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**[[2edu]] – hKIFL 22 C-terminal – NMR<br />
**[[2edu]] – hKIFL 22 C-terminal – NMR<br />
**[[3bfn]] – hKIFL 22 MD<br />
**[[6nje]] – hKIFL 22 MD +ADP<br />
**[[6nje]] – hKIFL 22 MD +ADP<br />


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