9hgj: Difference between revisions

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'''Unreleased structure'''


The entry 9hgj is ON HOLD
==HSV-1 Origin Binding Protein in complex with double-stranded DNA recognition sequence OriS and non-hydrolyzable ATP analog==
 
<StructureSection load='9hgj' size='340' side='right'caption='[[9hgj]], [[Resolution|resolution]] 3.53&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9hgj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1_strain_KOS Human alphaherpesvirus 1 strain KOS] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9HGJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9HGJ FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.53&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9hgj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9hgj OCA], [https://pdbe.org/9hgj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9hgj RCSB], [https://www.ebi.ac.uk/pdbsum/9hgj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9hgj ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/D3YPE9_HHV1F D3YPE9_HHV1F] Functions as a docking protein to recruit essential components of the viral replication machinery to viral DNA origins. In the presence of the major DNA-binding protein, opens dsDNA leading to a conformational change in the origin that facilitates DNA unwinding and subsequent replication.[ARBA:ARBA00025279]
__TOC__
</StructureSection>
[[Category: Human alphaherpesvirus 1 strain KOS]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Elias P]]
[[Category: Grunewald K]]
[[Category: Gustavsson E]]
[[Category: Hallberg BM]]

Latest revision as of 09:08, 22 October 2025

HSV-1 Origin Binding Protein in complex with double-stranded DNA recognition sequence OriS and non-hydrolyzable ATP analog

9hgj, resolution 3.53Å

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