8z8b: Difference between revisions
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==Cryo-EM structure of human HCAR1-Gi complex without ligand (apo state)== | |||
<StructureSection load='8z8b' size='340' side='right'caption='[[8z8b]], [[Resolution|resolution]] 2.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8z8b]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z8B OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z8B FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.65Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z8b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z8b OCA], [https://pdbe.org/8z8b PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z8b RCSB], [https://www.ebi.ac.uk/pdbsum/8z8b PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z8b ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/HCAR1_HUMAN HCAR1_HUMAN] Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.<ref>PMID:19047060</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Gao M]] | |||
[[Category: Ma X]] | |||
[[Category: Mao C]] | |||
[[Category: Zang S]] | |||
[[Category: Zhang Y]] | |||
[[Category: Zhu Y]] | |||
Latest revision as of 07:07, 29 October 2025
Cryo-EM structure of human HCAR1-Gi complex without ligand (apo state)
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