9if3: Difference between revisions

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'''Unreleased structure'''


The entry 9if3 is ON HOLD  until Paper Publication
==Structure of YIUA from Yersinia ruckeri with Iron and DHB-L-Arg-L-Ser==
<StructureSection load='9if3' size='340' side='right'caption='[[9if3]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[9if3]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Yersinia_ruckeri Yersinia ruckeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IF3 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1I15:(2~{S})-2-[[(2~{S})-2-[[2,3-bis(oxidanyl)phenyl]carbonylamino]-5-carbamimidamido-pentanoyl]amino]-3-oxidanyl-propanoic+acid'>A1I15</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9if3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9if3 OCA], [https://pdbe.org/9if3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9if3 RCSB], [https://www.ebi.ac.uk/pdbsum/9if3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9if3 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/A0A085U4N5_YERRU A0A085U4N5_YERRU]
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The marine pathogen Yersinia ruckeri synthesizes the tri-catecholate siderophore ruckerbactin, Rb, (DHB-(L)Arg-(L)Ser)(3), to acquire iron during infection. Its biosynthetic gene cluster encodes a single periplasmic binding protein, RupB, which surprisingly does not bind Fe(III)-Rb nor the Fe(III) complexes of its hydrolysis products, the di- and mono-catecholate siderophores Rb(DC) and Rb(MC), with biologically relevant affinities. Instead, the periplasmic binding protein YiuA, encoded in a different region of the chromosome, binds the 1 : 2 Fe(III) complex of the mono-catecholate Rb(MC), Fe(III)-(Rb(MC))(2). YiuA is the first periplasmic binding protein (PBP) to selectively recognize a mono-catecholate siderophore, the structural basis of which was illuminated through X-ray crystallography of YiuA bound to Fe(III)-(Rb(MC))(2).


Authors: Thompson, S., Thomsen, E., Duhme-Klair, A., Butler, A., Grogan, G.
Yersinia ruckeri YRB periplasmic binding protein YiuA selectively recognizes a Fe(III)-mono-catecholate siderophore.,Thomsen E, Thompson S, Stow PR, Cukor M, Grogan G, Duhme-Klair AK, Butler A Chem Commun (Camb). 2025 Oct 16. doi: 10.1039/d5cc05103g. PMID:41098114<ref>PMID:41098114</ref>


Description: Structure of YIUA from Yersinia ruckeri with Iron and DHB-L-Arg-L-Ser
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
[[Category: Unreleased Structures]]
</div>
[[Category: Thomsen, E]]
<div class="pdbe-citations 9if3" style="background-color:#fffaf0;"></div>
[[Category: Thompson, S]]
== References ==
[[Category: Duhme-Klair, A]]
<references/>
[[Category: Grogan, G]]
__TOC__
[[Category: Butler, A]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Yersinia ruckeri]]
[[Category: Butler A]]
[[Category: Duhme-Klair A]]
[[Category: Grogan G]]
[[Category: Thompson S]]
[[Category: Thomsen E]]
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