9t0k: Difference between revisions

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'''Unreleased structure'''


The entry 9t0k is ON HOLD
==Catalase CryoEM Structure from Human erythrocyte at 1.87A resolution==
 
<StructureSection load='9t0k' size='340' side='right'caption='[[9t0k]], [[Resolution|resolution]] 1.87&Aring;' scene=''>
Authors: Li, J., Henderson, R., Russo, C.J., Wilson, H., Chen, S.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9t0k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9T0K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9T0K FirstGlance]. <br>
Description: Catalase CryoEM Structure from Human erythrocyte at 1.87A resolution
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 1.87&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
[[Category: Wilson, H]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9t0k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9t0k OCA], [https://pdbe.org/9t0k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9t0k RCSB], [https://www.ebi.ac.uk/pdbsum/9t0k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9t0k ProSAT]</span></td></tr>
[[Category: Russo, C.J]]
</table>
[[Category: Li, J]]
== Disease ==
[[Category: Henderson, R]]
[https://www.uniprot.org/uniprot/CATA_HUMAN CATA_HUMAN] Defects in CAT are the cause of acatalasemia (ACATLAS) [MIM:[https://omim.org/entry/614097 614097]. A metabolic disorder characterized by absence of catalase activity in red cells and is often associated with ulcerating oral lesions.<ref>PMID:2308162</ref>
[[Category: Chen, S]]
== Function ==
[https://www.uniprot.org/uniprot/CATA_HUMAN CATA_HUMAN] Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells.<ref>PMID:7882369</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Chen S]]
[[Category: Henderson R]]
[[Category: Li J]]
[[Category: Russo CJ]]
[[Category: Wilson H]]
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