9shd: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Structure of vaccinia virus A26 (residues 1-397) in complex with Fab 10M2146== | |||
<StructureSection load='9shd' size='340' side='right'caption='[[9shd]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9shd]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9SHD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9SHD FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9shd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9shd OCA], [https://pdbe.org/9shd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9shd RCSB], [https://www.ebi.ac.uk/pdbsum/9shd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9shd ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Battini | == Function == | ||
[https://www.uniprot.org/uniprot/PG153_VACCW PG153_VACCW] Envelop protein that mediates acid-dependent endocytosis into host cells (PubMed:20538855). Plays an important role in endocytic entry of the virus by acting as an acid-sensitive membrane fusion suppressor (PubMed:22278246, PubMed:31220181). Low pH in host endosomes triggers conformational changes to allow de-repression of viral fusion complex activity and membrane fusion within vesicles (PubMed:31220181). Plays also a role in bridging the mature virion with structural protein OPG152.<ref>PMID:20538855</ref> <ref>PMID:22278246</ref> <ref>PMID:31220181</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Lama glama]] | |||
[[Category: Large Structures]] | |||
[[Category: Vaccinia virus]] | |||
[[Category: Battini L]] | |||
[[Category: Guardado-Calvo P]] | |||
Latest revision as of 07:51, 19 November 2025
Structure of vaccinia virus A26 (residues 1-397) in complex with Fab 10M2146
| ||||||||||||
