Sandbox: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 38: | Line 38: | ||
Pelis, R.M. (2014). A plasma concentration of α-ketoglutarate influences | Pelis, R.M. (2014). A plasma concentration of α-ketoglutarate influences | ||
the kinetic interaction of ligands with organic anion transporter 1. Mol. | the kinetic interaction of ligands with organic anion transporter 1. Mol. | ||
Pharmacol. 86, 86–95. https://doi.org/10.1124/mol.114.091777.</ref> | Pharmacol. 86, 86–95. https://doi.org/10.1124/mol.114.091777.</ref>OAT1 also plays a key role in excreting waste from organic drug metabolism and | ||
contributes significantly to drug-drug interactions and drug disposition. However, the structural basis of specific | contributes significantly to drug-drug interactions and drug disposition. However, the structural basis of specific | ||
substrate and inhibitor transport by human OAT1 (hOAT1) has remained elusive. Here are four | substrate and inhibitor transport by human OAT1 (hOAT1) has remained elusive. Here are four | ||