9iby: Difference between revisions
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==Crystal structure of Zika Virus NS2B-NS3 protease in complex with compound 2== | |||
<StructureSection load='9iby' size='340' side='right'caption='[[9iby]], [[Resolution|resolution]] 2.29Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9iby]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Zika_virus Zika virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9IBY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9IBY FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.291Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1I16:1-[3-[[5-(4,6-dimethylpyrimidin-5-yl)pyridin-2-yl]methyl]-1,2,3-oxadiazol-3-ium-5-yl]-3-[3-(trifluoromethyl)phenyl]urea'>A1I16</scene>, <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene></td></tr> | ||
[[Category: Ontario | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9iby FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9iby OCA], [https://pdbe.org/9iby PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9iby RCSB], [https://www.ebi.ac.uk/pdbsum/9iby PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9iby ProSAT]</span></td></tr> | ||
[[Category: Torrente | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/A0A140DLX4_ZIKV A0A140DLX4_ZIKV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Zika virus]] | |||
[[Category: Ontario JM]] | |||
[[Category: Torrente E]] | |||
Latest revision as of 19:17, 4 December 2025
Crystal structure of Zika Virus NS2B-NS3 protease in complex with compound 2
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