9kt2: Difference between revisions

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'''Unreleased structure'''


The entry 9kt2 is ON HOLD  until Paper Publication
==The crystal structure of BD1 in complex with BDS4==
 
<StructureSection load='9kt2' size='340' side='right'caption='[[9kt2]], [[Resolution|resolution]] 1.46&Aring;' scene=''>
Authors: Zhang, Z.M., Wang, Y.Q.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9kt2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9KT2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9KT2 FirstGlance]. <br>
Description: The crystal structure of BD1 in complex with BDS4
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.4620651&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EMP:(2~{S})-2-azanyl-6-[(1~{S})-7-[6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1~{S})-1-pyridin-2-ylethyl]pyrrolo[3,2-b]pyridin-3-yl]-3-methylidene-1-oxidanyl-1~{H}-isoindol-2-yl]hexanoic+acid'>A1EMP</scene></td></tr>
[[Category: Wang, Y.Q]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9kt2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9kt2 OCA], [https://pdbe.org/9kt2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9kt2 RCSB], [https://www.ebi.ac.uk/pdbsum/9kt2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9kt2 ProSAT]</span></td></tr>
[[Category: Zhang, Z.M]]
</table>
== Disease ==
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.<ref>PMID:12543779</ref> <ref>PMID:11733348</ref>
== Function ==
[https://www.uniprot.org/uniprot/BRD4_HUMAN BRD4_HUMAN] Plays a role in a process governing chromosomal dynamics during mitosis (By similarity).
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Wang YQ]]
[[Category: Zhang ZM]]
Retrieved from "https://proteopedia.org/9kt2"