9vi9: Difference between revisions
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==Cryo-EM Structure of NPFFR1 in complex with peptide RFRP-3== | |||
<StructureSection load='9vi9' size='340' side='right'caption='[[9vi9]], [[Resolution|resolution]] 3.02Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9vi9]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9VI9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9VI9 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.02Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9vi9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9vi9 OCA], [https://pdbe.org/9vi9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9vi9 RCSB], [https://www.ebi.ac.uk/pdbsum/9vi9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9vi9 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NPFF1_HUMAN NPFF1_HUMAN] Receptor for NPAF (A-18-F-amide) and NPFF (F-8-F-amide) neuropeptides, also known as morphine-modulating peptides. Can also be activated by a variety of naturally occurring or synthetic FMRF-amide like ligands. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.<ref>PMID:11024015</ref> <ref>PMID:11025660</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Na M]] | |||
[[Category: Xu F]] | |||
Latest revision as of 19:41, 4 December 2025
Cryo-EM Structure of NPFFR1 in complex with peptide RFRP-3
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