9bbj: Difference between revisions
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==M. tuberculosis ClpC1-NTD complexed with a click chemistry analog of Rufomycin== | |||
<StructureSection load='9bbj' size='340' side='right'caption='[[9bbj]], [[Resolution|resolution]] 2.56Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9bbj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9BBJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9BBJ FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.56Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1AL8:1-(2-methylbut-3-en-2-yl)-L-tryptophan'>A1AL8</scene>, <scene name='pdbligand=A1AMB:(2~{S})-2-azanyl-3-(1,2,3-triazol-1-yl)propanoic+acid'>A1AMB</scene>, <scene name='pdbligand=A1AMC:5-hydroxy-N-methyl-L-norvaline'>A1AMC</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=NLE:NORLEUCINE'>NLE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9bbj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9bbj OCA], [https://pdbe.org/9bbj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9bbj RCSB], [https://www.ebi.ac.uk/pdbsum/9bbj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9bbj ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CLPC1_MYCTU CLPC1_MYCTU] ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity). Degrades anti-sigma-E factor RseA in the presence of ClpP2. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Synthetic construct]] | |||
[[Category: Abad-Zapatero C]] | |||
[[Category: Ratia K]] | |||
Revision as of 08:01, 11 December 2025
M. tuberculosis ClpC1-NTD complexed with a click chemistry analog of Rufomycin
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