9jf3: Difference between revisions
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The | ==The complex structure of 0086-0043 and NET determined with Cryo-EM.== | ||
<StructureSection load='9jf3' size='340' side='right'caption='[[9jf3]], [[Resolution|resolution]] 2.87Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9jf3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9JF3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9JF3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.87Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EBO:2-isoquinolin-2-ium-2-yl-1-phenyl-ethanone'>A1EBO</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9jf3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9jf3 OCA], [https://pdbe.org/9jf3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9jf3 RCSB], [https://www.ebi.ac.uk/pdbsum/9jf3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9jf3 ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: | == Disease == | ||
[[Category: Tan | [https://www.uniprot.org/uniprot/SC6A2_HUMAN SC6A2_HUMAN] Postural orthostatic tachycardia syndrome due to NET deficiency. The disease is caused by variants affecting the gene represented in this entry. | ||
[[Category: | == Function == | ||
[[Category: | [https://www.uniprot.org/uniprot/SC6A2_HUMAN SC6A2_HUMAN] Mediates sodium- and chloride-dependent transport of norepinephrine (also known as noradrenaline) (PubMed:2008212, PubMed:8125921). Can also mediate sodium- and chloride-dependent transport of dopamine (PubMed:11093780, PubMed:8125921).<ref>PMID:11093780</ref> <ref>PMID:2008212</ref> <ref>PMID:8125921</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Gao B]] | |||
[[Category: Jia YJ]] | |||
[[Category: Lan YY]] | |||
[[Category: Tan JX]] | |||
[[Category: Yan CY]] | |||
[[Category: Zhang W]] | |||
Latest revision as of 05:15, 24 December 2025
The complex structure of 0086-0043 and NET determined with Cryo-EM.
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