9l65: Difference between revisions
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==A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures== | |||
<StructureSection load='9l65' size='340' side='right'caption='[[9l65]], [[Resolution|resolution]] 1.99Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9l65]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9L65 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9L65 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EJN:[2,5-bis(oxidanylidene)pyrrolidin-1-yl]+18-(2,3-dimethylimidazol-1-ium-1-yl)octadecanoate'>A1EJN</scene></td></tr> | ||
[[Category: Fang | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9l65 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9l65 OCA], [https://pdbe.org/9l65 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9l65 RCSB], [https://www.ebi.ac.uk/pdbsum/9l65 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9l65 ProSAT]</span></td></tr> | ||
[[Category: Jiang | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/FUT8_HUMAN FUT8_HUMAN] Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.<ref>PMID:9133635</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Fang P]] | |||
[[Category: Jiang J]] | |||
Latest revision as of 11:32, 7 January 2026
A novel allosteric covalent inhibitory site of fucosyltransferase 8 revealed by crystal structures
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