9zop: Difference between revisions

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'''Unreleased structure'''


The entry 9zop is ON HOLD
==OXA-23-JDB/PQ-1-219, 3 min soak==
 
<StructureSection load='9zop' size='340' side='right'caption='[[9zop]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
Authors: Smith, C.A., Maggiolo, A.M., Vakulenko, S.B., Toth, M.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9zop]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Acinetobacter_baumannii Acinetobacter baumannii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9ZOP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9ZOP FirstGlance]. <br>
Description: OXA-23-JDB/PQ-1-219, 3 min soak
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=KCX:LYSINE+NZ-CARBOXYLIC+ACID'>KCX</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Vakulenko, S.B]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9zop FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9zop OCA], [https://pdbe.org/9zop PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9zop RCSB], [https://www.ebi.ac.uk/pdbsum/9zop PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9zop ProSAT]</span></td></tr>
[[Category: Maggiolo, A.M]]
</table>
[[Category: Toth, M]]
== Function ==
[[Category: Smith, C.A]]
[https://www.uniprot.org/uniprot/BLO23_ACIBA BLO23_ACIBA] Class D beta-lactamase which confers resistance to the beta-lactam antibiotics, including ampicillin, and carbapenems such as imipenem and meropenem (PubMed:18725452, PubMed:20194701, PubMed:24012371, PubMed:30530607, PubMed:35420470). Acts via hydrolysis of the beta-lactam ring (PubMed:23877677, PubMed:24012371, PubMed:30530607, PubMed:35420470). Has penicillin-, cephalosporin- and carbapenem-hydrolyzing activities, but lacks ceftazidime-hydrolyzing activity (PubMed:23877677, PubMed:24012371, PubMed:30530607, PubMed:35420470).<ref>PMID:18725452</ref> <ref>PMID:20194701</ref> <ref>PMID:23877677</ref> <ref>PMID:24012371</ref> <ref>PMID:30530607</ref> <ref>PMID:35420470</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Acinetobacter baumannii]]
[[Category: Large Structures]]
[[Category: Maggiolo AM]]
[[Category: Smith CA]]
[[Category: Toth M]]
[[Category: Vakulenko SB]]
Retrieved from "https://proteopedia.org/9zop"