9yzz: Difference between revisions

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<table><tr><td colspan='2'>[[9yzz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9YZZ FirstGlance]. <br>
<table><tr><td colspan='2'>[[9yzz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YZZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9YZZ FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.42&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1CZS:N-({[4-({N-[3-(2,5-dioxopyrrolidin-1-yl)propanoyl]-L-alanyl-L-alanyl}amino)phenyl]methoxy}carbonyl)-N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino}-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl}-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide'>A1CZS</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1CZS:[4-[[(2~{S})-2-[[(2~{S})-2-[3-[2,5-bis(oxidanylidene)pyrrolidin-1-yl]propanoylamino]propanoyl]amino]propanoyl]amino]phenyl]methyl+~{N}-[(2~{S})-1-[[(2~{S})-1-[[(3~{R},4~{S},5~{S})-3-methoxy-1-[(2~{S})-2-[(1~{R},2~{R})-1-methoxy-2-methyl-3-oxidanylidene-3-[[(1~{S},2~{R})-1-oxidanyl-1-phenyl-propan-2-yl]amino]propyl]pyrrolidin-1-yl]-5-methyl-1-oxidanylidene-heptan-4-yl]-methyl-amino]-3-methyl-1-oxidanylidene-butan-2-yl]amino]-3-methyl-1-oxidanylidene-butan-2-yl]-~{N}-methyl-carbamate'>A1CZS</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9yzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9yzz OCA], [https://pdbe.org/9yzz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9yzz RCSB], [https://www.ebi.ac.uk/pdbsum/9yzz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9yzz ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9yzz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9yzz OCA], [https://pdbe.org/9yzz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9yzz RCSB], [https://www.ebi.ac.uk/pdbsum/9yzz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9yzz ProSAT]</span></td></tr>
</table>
</table>

Latest revision as of 11:34, 10 February 2026

Crystal structure of Trastuzumab Fab conjugated to Linker-Payload

9yzz, resolution 2.42Å

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