9r8t: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
m Protected "9r8t" [edit=sysop:move=sysop]
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
Line 1: Line 1:
'''Unreleased structure'''


The entry 9r8t is ON HOLD  until Paper Publication
==Cryo-EM structure of the E3 ligase HECTD3==
 
<StructureSection load='9r8t' size='340' side='right'caption='[[9r8t]], [[Resolution|resolution]] 6.06&Aring;' scene=''>
Authors: Esposito, D., Huber, J., Maslen, S., Rittinger, K.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9r8t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9R8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9R8T FirstGlance]. <br>
Description: Cryo-EM structure of the E3 ligase HECTD3
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 6.06&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9r8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9r8t OCA], [https://pdbe.org/9r8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9r8t RCSB], [https://www.ebi.ac.uk/pdbsum/9r8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9r8t ProSAT]</span></td></tr>
[[Category: Maslen, S]]
</table>
[[Category: Huber, J]]
== Function ==
[[Category: Rittinger, K]]
[https://www.uniprot.org/uniprot/HECD3_HUMAN HECD3_HUMAN] E3 ubiquitin ligases accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of TRIOBP and its subsequent proteasomal degradation, thus facilitating cell cycle progression by regulating the turn-over of TRIOBP. Mediates also ubiquitination of STX8 (By similarity).[UniProtKB:Q3U487]<ref>PMID:18194665</ref>
[[Category: Esposito, D]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Esposito D]]
[[Category: Huber J]]
[[Category: Maslen S]]
[[Category: Rittinger K]]
Retrieved from "https://proteopedia.org/9r8t"