9j5n: Difference between revisions
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==Pathogen effector forms a phosphatase holoenzyme complex with host core enzyme to promote disease== | |||
<StructureSection load='9j5n' size='340' side='right'caption='[[9j5n]], [[Resolution|resolution]] 4.30Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9j5n]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Phytophthora_sojae Phytophthora sojae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9J5N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9J5N FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.3Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> | ||
[[Category: Wang | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9j5n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9j5n OCA], [https://pdbe.org/9j5n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9j5n RCSB], [https://www.ebi.ac.uk/pdbsum/9j5n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9j5n ProSAT]</span></td></tr> | ||
[[Category: Wang | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/PSR2_PHYSO PSR2_PHYSO] Secreted effector that possesses RNA silencing suppression activity by inhibiting the biogenesis of small RNAs in the host plant to promote enhanced susceptibility of host to the pathogen during infection (PubMed:23377181, PubMed:25387135, PubMed:30595554). Interferes with secondary siRNA production by associating with host dsRNA-binding protein DRB4 (PubMed:30595554). Inhibits the host salicylic acid pathway during infection (PubMed:25387135).<ref>PMID:23377181</ref> <ref>PMID:25387135</ref> <ref>PMID:30595554</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arabidopsis thaliana]] | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Phytophthora sojae]] | |||
[[Category: Wang JL]] | |||
[[Category: Wang YL]] | |||
Latest revision as of 07:43, 4 March 2026
Pathogen effector forms a phosphatase holoenzyme complex with host core enzyme to promote disease
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