9m0l: Difference between revisions

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'''Unreleased structure'''


The entry 9m0l is ON HOLD  until Paper Publication
==Crystal structure of Arabidopsis thaliana sulfotransferase SOT18 complexed with glucoraphanin precursor involved in glucosinolate biosynthesis==
 
<StructureSection load='9m0l' size='340' side='right'caption='[[9m0l]], [[Resolution|resolution]] 1.39&Aring;' scene=''>
Authors: Hirata, R., Moriyasu, T., Iwamoto, Y., Teramoto, T., Kakuta, Y.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9m0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9M0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9M0L FirstGlance]. <br>
Description: Crystal structure of Arabidopsis thaliana sulfotransferase SOT18 complexed with glucoraphanin precursor involved in glucosinolate biosynthesis
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.39&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1L7V:[(2~{S},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]+(1~{Z})-5-[methyl(oxidanyl)-$l^{3}-sulfanyl]-~{N}-oxidanyl-pentanimidothioate'>A1L7V</scene>, <scene name='pdbligand=A3P:ADENOSINE-3-5-DIPHOSPHATE'>A3P</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
[[Category: Iwamoto, Y]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9m0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9m0l OCA], [https://pdbe.org/9m0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9m0l RCSB], [https://www.ebi.ac.uk/pdbsum/9m0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9m0l ProSAT]</span></td></tr>
[[Category: Moriyasu, T]]
</table>
[[Category: Kakuta, Y]]
== Function ==
[[Category: Hirata, R]]
[https://www.uniprot.org/uniprot/SOT18_ARATH SOT18_ARATH] Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of desulfo-glucosinolates (dsGSs), the final step in the biosynthesis of the glucosinolate core structure. Preferred substrate are the long-chain desulfo-glucosinolates, 7-methylthioheptyl and 8-methylthiooctyl, derived from methionine. Substrate preference is desulfo-benzyl glucosinolate > desulfo-4-methylthiobutyl glucosinolate > desulfo-6-methylthiohexyl glucosinolate > desulfo-3-methylthiopropyl glucosinolate > desulfo-indol-3-yl methyl glucosinolate > desulfo-singrin > desulfo-3-butenyl glucosinolate.<ref>PMID:15358770</ref> <ref>PMID:15866872</ref> <ref>PMID:16367753</ref> <ref>PMID:19077143</ref> <ref>PMID:21281472</ref>
[[Category: Teramoto, T]]
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Large Structures]]
[[Category: Hirata R]]
[[Category: Iwamoto Y]]
[[Category: Kakuta Y]]
[[Category: Moriyasu T]]
[[Category: Teramoto T]]

Latest revision as of 07:46, 4 March 2026

Crystal structure of Arabidopsis thaliana sulfotransferase SOT18 complexed with glucoraphanin precursor involved in glucosinolate biosynthesis

9m0l, resolution 1.39Å

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