9ybn: Difference between revisions
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==2.53A cryo-EM structure of RNA-directed RNA polymerase L of Crimean-Congo hemorrhagic fever virus (RNA bound)== | |||
<StructureSection load='9ybn' size='340' side='right'caption='[[9ybn]], [[Resolution|resolution]] 2.53Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9ybn]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Crimean-Congo_hemorrhagic_fever_virus_strain_IbAr10200 Crimean-Congo hemorrhagic fever virus strain IbAr10200]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9YBN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9YBN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.53Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ybn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ybn OCA], [https://pdbe.org/9ybn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ybn RCSB], [https://www.ebi.ac.uk/pdbsum/9ybn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ybn ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/L_CCHFI L_CCHFI] Displays RNA-directed RNA polymerase, deubiquitinating and deISGylase activities. RNA-dependent RNA polymerase is responsible for replication and transcription of the viral RNA genome. The deubiquitinating activity cleaves both ubiquitinated and ISGylated products and may therefore regulate ubiquitin and ISG15 dependent innate immunity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Crimean-Congo hemorrhagic fever virus strain IbAr10200]] | |||
[[Category: Large Structures]] | |||
[[Category: Liu B]] | |||
[[Category: Wang D]] | |||
[[Category: Yang G]] | |||
Latest revision as of 08:00, 4 March 2026
2.53A cryo-EM structure of RNA-directed RNA polymerase L of Crimean-Congo hemorrhagic fever virus (RNA bound)
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