9m77: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The ~~entry~~ 9m77 is ~~ON HOLD until Paper Publication~~

==The activated state of human UHRF1 bound to a mononucleosome, with the finger loop ordered and linker 4 disordered.==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9m77]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9M77 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9M77 FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9m77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9m77 OCA], [https://pdbe.org/9m77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9m77 RCSB], [https://www.ebi.ac.uk/pdbsum/9m77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9m77 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: Xenopus laevis]]

[[Category: Baradaran R]]

[[Category: Fischle W]]

[[Category: Naschberger A]]

[[Category: Sayed A]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9m77 is ON HOLD  until Paper Publication
+==The activated state of human UHRF1 bound to a mononucleosome, with the finger loop ordered and linker 4 disordered.==
+<StructureSection load='9m77' size='340' side='right'caption='[[9m77]], [[Resolution|resolution]] 3.70&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9m77]] is a 11 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9M77 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9M77 FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.7&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CM:5-METHYL-2-DEOXY-CYTIDINE-5-MONOPHOSPHATE'>5CM</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9m77 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9m77 OCA], [https://pdbe.org/9m77 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9m77 RCSB], [https://www.ebi.ac.uk/pdbsum/9m77 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9m77 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/H4_XENLA H4_XENLA] Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
+__TOC__
+</StructureSection>
+[[Category: Homo sapiens]]
+[[Category: Large Structures]]
+[[Category: Xenopus laevis]]
+[[Category: Baradaran R]]
+[[Category: Fischle W]]
+[[Category: Naschberger A]]
+[[Category: Sayed A]]