9qal: Difference between revisions

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'''Unreleased structure'''


The entry 9qal is ON HOLD until Paper Publication
==Solution NMR structure of Arkadia 2 RING domain==
 
<StructureSection load='9qal' size='340' side='right'caption='[[9qal]]' scene=''>
Authors: Marousis, K.D., Giannari, D., Seliami, A., Politi, M., Birkou, M., Bentrop, D., Episkopou, V., Spyroulias, G.A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9qal]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9QAL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9QAL FirstGlance]. <br>
Description: Solution NMR structure of Arkadia 2 RING domain
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, models</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[Category: Birkou, M]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9qal FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9qal OCA], [https://pdbe.org/9qal PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9qal RCSB], [https://www.ebi.ac.uk/pdbsum/9qal PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9qal ProSAT]</span></td></tr>
[[Category: Marousis, K.D]]
</table>
[[Category: Episkopou, V]]
== Function ==
[[Category: Seliami, A]]
[https://www.uniprot.org/uniprot/ARK2C_HUMAN ARK2C_HUMAN] E3 ubiquitin-protein ligase that acts as a regulator of motor axon elongation. Required for efficient motor axon extension in the dorsal forelimb by enhancing the transcriptional responses of the SMAD1/SMAD5/SMAD8 effectors, which are activated downstream of BMP. Acts by mediating ubiquitination and degradation of SMAD inhibitors such as SMAD6, SMAD7, SKI and SNON isoform of SKIL.[UniProtKB:E9QAU8]
[[Category: Bentrop, D]]
__TOC__
[[Category: Spyroulias, G.A]]
</StructureSection>
[[Category: Giannari, D]]
[[Category: Homo sapiens]]
[[Category: Politi, M]]
[[Category: Large Structures]]
[[Category: Bentrop D]]
[[Category: Birkou M]]
[[Category: Episkopou V]]
[[Category: Giannari D]]
[[Category: Marousis KD]]
[[Category: Politi M]]
[[Category: Seliami A]]
[[Category: Spyroulias GA]]
Retrieved from "https://proteopedia.org/9qal"