9t0a: Difference between revisions

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'''Unreleased structure'''


The entry 9t0a is ON HOLD  until Paper Publication
==X-ray structure of the complex between the catalytic domain of CDC25B C473S and 3-O-methylfluorescein phosphate (3-OMFP)==
 
<StructureSection load='9t0a' size='340' side='right'caption='[[9t0a]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9t0a]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9T0A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9T0A FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1JSP:[(1~{S})-6-methoxy-3-oxidanylidene-spiro[2-benzofuran-1,9-xanthene]-3-yl]+dihydrogen+phosphate'>A1JSP</scene>, <scene name='pdbligand=A1JSQ:[(1~{R})-6-methoxy-3-oxidanylidene-spiro[2-benzofuran-1,9-xanthene]-3-yl]+dihydrogen+phosphate'>A1JSQ</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9t0a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9t0a OCA], [https://pdbe.org/9t0a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9t0a RCSB], [https://www.ebi.ac.uk/pdbsum/9t0a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9t0a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/MPIP2_HUMAN MPIP2_HUMAN] Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.<ref>PMID:17332740</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Napolitano V]]
[[Category: Sica F]]
[[Category: Troisi R]]
Retrieved from "https://proteopedia.org/9t0a"