9e3i: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

The ~~entry~~ 9e3i is ~~ON HOLD until Paper Publication~~

==The primed conformation of herpes simplex virus type 1 (HSV-1) glycoprotein B (gB)==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[9e3i]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1_strain_F Human alphaherpesvirus 1 strain F]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9E3I OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=9E3I FirstGlance].

~~Description~~:

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9Å</td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=9e3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9e3i OCA], [https://pdbe.org/9e3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9e3i RCSB], [https://www.ebi.ac.uk/pdbsum/9e3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9e3i ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/GB_HHV11 GB_HHV11] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress (By similarity). Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation).[HAMAP-Rule:MF_04032]<ref>PMID:15596825</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Human alphaherpesvirus 1 strain F]]

[[Category: Large Structures]]

[[Category: Dai X]]

[[Category: Mou Z]]

[[Category: Wang S]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 9e3i is ON HOLD  until Paper Publication
+==The primed conformation of herpes simplex virus type 1 (HSV-1) glycoprotein B (gB)==
+<StructureSection load='9e3i' size='340' side='right'caption='[[9e3i]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[9e3i]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_alphaherpesvirus_1_strain_F Human alphaherpesvirus 1 strain F]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9E3I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9E3I FirstGlance]. <br>
-Description:
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9e3i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9e3i OCA], [https://pdbe.org/9e3i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9e3i RCSB], [https://www.ebi.ac.uk/pdbsum/9e3i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9e3i ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/GB_HHV11 GB_HHV11] Envelope glycoprotein that forms spikes at the surface of virion envelope. Essential for the initial attachment to heparan sulfate moieties of the host cell surface proteoglycans. Involved in fusion of viral and cellular membranes leading to virus entry into the host cell. Following initial binding to its host receptors, membrane fusion is mediated by the fusion machinery composed at least of gB and the heterodimer gH/gL. May be involved in the fusion between the virion envelope and the outer nuclear membrane during virion egress (By similarity). Also plays a role, together with gK, in virus-induced cell-to-cell fusion (syncytia formation).[HAMAP-Rule:MF_04032]<ref>PMID:15596825</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Human alphaherpesvirus 1 strain F]]
+[[Category: Large Structures]]
+[[Category: Dai X]]
+[[Category: Mou Z]]
+[[Category: Wang S]]