GTPase KRas 3D structures: Difference between revisions
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
{{#tree:id=OrganizedByTopic|openlevels=0| | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
*GTPase KRas apo binary complex with nucleotide | *GTPase KRas apo binary complex with nucleotide | ||
**[[5uk9]] – hKRas + GCP + GDP – human <br /> | **[[5uk9]] – hKRas + GCP + GDP – human <br /> | ||
**[[5vq2]] – hKRas + GTP <br /> | **[[5vq2]] – hKRas + GTP <br /> | ||
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**[[9o0r]], [[9o0s]] – hKRas + drug + GDP <br /> | **[[9o0r]], [[9o0s]] – hKRas + drug + GDP <br /> | ||
**[[7mqu]] – hKRas + drug + GDP - NMR<br /> | **[[7mqu]] – hKRas + drug + GDP - NMR<br /> | ||
*GTPase KRas apo complex with inhibitor | *GTPase KRas apo complex with inhibitor | ||
**[[5kyk]] – hKRas + inhibitor <br /> | **[[5kyk]] – hKRas + inhibitor <br /> | ||
**[[6v5l]], [[7tle]], [[8afb]], [[8afc]], [[8afd]], [[8azr]], [[8azv]], [[8jhl]], [[8onv]], [[8s8c]], [[9bai]], [[9bak]], [[9baj]], [[9qpz]] – hKRas + GDP + inhibitor <br /> | **[[6v5l]], [[7tle]], [[8afb]], [[8afc]], [[8afd]], [[8azr]], [[8azv]], [[8jhl]], [[8onv]], [[8s8c]], [[9bai]], [[9bak]], [[9baj]], [[9qpz]] – hKRas + GDP + inhibitor <br /> | ||
*GTPase KRas apo complex with protein | *GTPase KRas apo complex with protein | ||
**[[6h46]] – hKRas + darpin K13 + GDP <br /> | **[[6h46]] – hKRas + darpin K13 + GDP <br /> | ||
**[[6h47]] – hKRas + darpin K19 <br /> | **[[6h47]] – hKRas + darpin K19 <br /> | ||
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**[[6yr8]], [[6yxw]], [[7ny8]] – hKRas + affirmer K6 + GDP <br /> | **[[6yr8]], [[6yxw]], [[7ny8]] – hKRas + affirmer K6 + GDP <br /> | ||
**[[8rro]] – hKRas + Tcr + HLA + microglobulin + drug + GNP <br /> | **[[8rro]] – hKRas + Tcr + HLA + microglobulin + drug + GNP <br /> | ||
*GTPase KRas4A apo | *GTPase KRas4A apo | ||
**[[8t72]] – hKRas + PNP<br /> | **[[8t72]] – hKRas + PNP<br /> | ||
**[[8t71]] – hKRas + GDP<br /> | **[[8t71]] – hKRas + GDP<br /> | ||
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**[[7vvb]] – hKRas + SIN1 + PNP<br /> | **[[7vvb]] – hKRas + SIN1 + PNP<br /> | ||
**[[9g0y]], [[9g4b]], [[9ggt]], [[9ggu]], [[9ggv]], [[9ggw]], [[9ggx]], [[9ggy]], [[9ggz]], [[9gh0]], [[9gh1]], [[9gh2]] – hKRas + GDP + inhibitor<br /> | **[[9g0y]], [[9g4b]], [[9ggt]], [[9ggu]], [[9ggv]], [[9ggw]], [[9ggx]], [[9ggy]], [[9ggz]], [[9gh0]], [[9gh1]], [[9gh2]] – hKRas + GDP + inhibitor<br /> | ||
*GTPase KRas2B apo | *GTPase KRas2B apo | ||
**[[7kyz]] – hKRas + GDP - NMR<br /> | **[[7kyz]] – hKRas + GDP - NMR<br /> | ||
**[[9gtk]] – hKRas + Darpin + GDP<br /> | **[[9gtk]] – hKRas + Darpin + GDP<br /> | ||
*GTPase KRas4B apo | *GTPase KRas4B apo | ||
**[[6m9w]], [[8ecr]] – hKRas + GDP<br /> | **[[6m9w]], [[8ecr]] – hKRas + GDP<br /> | ||
**[[6w4e]] – hKRas + GDP - NMR<br /> | **[[6w4e]] – hKRas + GDP - NMR<br /> | ||
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**[[6w4f]] – hKRas + apolipoprotein + GDP - NMR<br /> | **[[6w4f]] – hKRas + apolipoprotein + GDP - NMR<br /> | ||
**[[6vjj]], [[6xhb]], [[6xi7]] – hKRas + Raf1/CRaf + GNP | **[[6vjj]], [[6xhb]], [[6xi7]] – hKRas + Raf1/CRaf + GNP | ||
*GTPase KRasX2 apo | *GTPase KRasX2 apo | ||
**[[8dgs]], [[8dgt]] – hKRas + MKK1 + B-Raf + 14-3-3 protein zeta + ATPgS – Cryo EM<br /> | **[[8dgs]], [[8dgt]] – hKRas + MKK1 + B-Raf + 14-3-3 protein zeta + ATPgS – Cryo EM<br /> | ||
*GTPase KRas with oncogenic mutated 12G binary complex with nucleotide | *GTPase KRas with oncogenic mutated 12G binary complex with nucleotide | ||
**[[5vpi]], [[5vpz]], [[5vq6]], [[6mnx]] – hKRas (mutant) + GTP <br /> | **[[5vpi]], [[5vpz]], [[5vq6]], [[6mnx]] – hKRas (mutant) + GTP <br /> | ||
**[[3gft]], [[6mta]] – hKRas (mutant) + GTP analog <br /> | **[[3gft]], [[6mta]] – hKRas (mutant) + GTP analog <br /> | ||
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**[[4dsn]], [[6bp1]], [[6quu]] – hKRas (mutant) + GCP <br /> | **[[4dsn]], [[6bp1]], [[6quu]] – hKRas (mutant) + GCP <br /> | ||
**[[7lz5]] – hKRas (mutant) + GMPPCP <br /> | **[[7lz5]] – hKRas (mutant) + GMPPCP <br /> | ||
*GTPase KRas with oncogenic mutated 12G complex with inhibitor | *GTPase KRas with oncogenic mutated 12G complex with inhibitor | ||
**[[4dso]] – hKRas (mutant) + inhibitor + GSP <br /> | **[[4dso]] – hKRas (mutant) + inhibitor + GSP <br /> | ||
**[[4dst]], [[6gj5]], [[6gj6]], [[6gj7]], [[6gj8]], [[6quv]], [[6quw]], [[6qux]] – hKRas (mutant) + inhibitor + GCP <br /> | **[[4dst]], [[6gj5]], [[6gj6]], [[6gj7]], [[6gj8]], [[6quv]], [[6quw]], [[6qux]] – hKRas (mutant) + inhibitor + GCP <br /> | ||
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**[[9usb]] – hKRas (mutant) + GPPNP + inhibitor <br /> | **[[9usb]] – hKRas (mutant) + GPPNP + inhibitor <br /> | ||
**[[5v71]], [[5v9l]], [[6t5v]] – hKRas (mutant) + GDP + quinazoline inhibitor <br /> | **[[5v71]], [[5v9l]], [[6t5v]] – hKRas (mutant) + GDP + quinazoline inhibitor <br /> | ||
*GTPase KRas with oncogenic mutated 12G complex with protein | *GTPase KRas with oncogenic mutated 12G complex with protein | ||
**[[5wha]], [[5whb]] – hKRas (mutant) + miniprotein + GDP <br /> | **[[5wha]], [[5whb]] – hKRas (mutant) + miniprotein + GDP <br /> | ||
**[[5whe]], [[5wlb]], [[5wpl]], [[5wpm]] – hKRas (mutant) + miniprotein + GNP <br /> | **[[5whe]], [[5wlb]], [[5wpl]], [[5wpm]] – hKRas (mutant) + miniprotein + GNP <br /> | ||
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**[[9bg5]], [[9bg6]], [[9bga]], [[9bgb]], [[9bgc]], [[9ct8]], [[9ct9]], [[9cta]], [[9ctb]] – hKRas (mutant) + PPIASE + drug + GNP <br /> | **[[9bg5]], [[9bg6]], [[9bga]], [[9bgb]], [[9bgc]], [[9ct8]], [[9ct9]], [[9cta]], [[9ctb]] – hKRas (mutant) + PPIASE + drug + GNP <br /> | ||
**[[6t5u]] – KRas (mutant) + V-ki-ras2 + inhibitor + GDP -hedgehog <br /> | **[[6t5u]] – KRas (mutant) + V-ki-ras2 + inhibitor + GDP -hedgehog <br /> | ||
*GTPase KRas4A with oncogenic mutated 12G | *GTPase KRas4A with oncogenic mutated 12G | ||
**[[8t73]] – hKRas (mutant) + GDP<br /> | **[[8t73]] – hKRas (mutant) + GDP<br /> | ||
*GTPase KRas4B with oncogenic mutated 12G | *GTPase KRas4B with oncogenic mutated 12G | ||
**[[7t1f]], [[8blr]], [[8cpr]], [[8edy]], [[8eer]] – hKRas (mutant) + GDP<br /> | **[[7t1f]], [[8blr]], [[8cpr]], [[8edy]], [[8eer]] – hKRas (mutant) + GDP<br /> | ||
**[[6cu6]] – hKRas (mutant) + PNP<br /> | **[[6cu6]] – hKRas (mutant) + PNP<br /> | ||