Carboxypeptidase 3D structures

3D Structures of Carboxypeptidase

Updated on 29-March-2026

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• Carboxypeptidase A
  • 2v77 – hCPA1 – human
    
  • 5cpa, 1yme, 1cps, 1ee3, 1cpx, 1m4l – bCPA – bovine
    
  • 1arl – bCPA
    
  • 1arm, 1eel, 1ell, 1elm – bCPA Zn-substituted
    
  • 1k9x – PfCPA apo – Pyrococcus furiosus
    
  • 1ka2, 1ka4 - PfCPA Zn-substituted
    
  • 5wvu, 3hoa – CPA – Thermus thermophilus
    
  • 3dwc – CPA – Trypanosoma cruzi
    
  • 3g23 – CPA – Novosphingobium aromaticivorans
    
  • 4ox5 – SpCPA – Stretomyces pneumoniae
    
  • 5e3x – CPA – Fervidobacterium islandicum
    
  • 5giv – CPA – Deinococcus radiodurans
    
• CPA complex with small molecules
  • 2pcu – hCPA4 + peptide
    
  • 4uee, 6i6z, 4uez – hCPA1 + peptide inhibitor
    
  • 5om9 – hCPA1 + inhibitor
    
  • 3cpa – bCPA + glycyl-tyrosine
    
  • 1f57 – bCPA + cysteine
    
  • 1hdq, 1hdu, 1hee – bCPA + phenylalanine derivative
    
  • 6cpa, 7cpa, 8cpa – bCPA + phosphate derivative
    
  • 2scp, 1cbx, 1bav, 1iy7, 2rfh, 3fx6, 3fvl, 3hlp, 3huv, 3kgq – bCPA + inhibitor
    
  • 3i1u – bCPA + thiirane
    
  • 2ctb, 2ctc – bCPA + phenyl lactate
    
  • 4oxd – SpCP + peptidoglycan
    
• CPA complex with protein
  • 3fju – hCPA1 + ascaris inhibitor
    
  • 1dtd – hCPA2 + metallo-CP inhibitor
    
  • 2bo9 – hCPA4 hydrolase domain + latexin
    
  • 4bd9 - hCPA4 hydrolase domain + SMCI inhibitor
    
  • 4a94 – hCPA4 + nerita versicolor inhibitor
    
  • 1zlh – bCPA + tick inhibitor
    
  • 4cpa – bCPA + potato inhibitor
    
  • 2abz - bCPA + metallo-CP inhibitor
    
• Procarboxypeptidase A
  • 1aye – hPCPA2
    
  • 1o6x – hPCPA2 activation domain – NMR
    
  • 2boa – hPCPA4
    
  • 1fon – bPCPA subunit III
    
  • 1pyt – bPCPA + proproteinase E + chymotrypsinogen C
    
  • 1jqg – PCPA – Cotton bollworm
    
• Carboxypeptidase B
  • 3d66 – hCPB 2
    
  • 3d68 – hCPB 2 (mutant)
    
  • 3lms – hCPB 2 + protein inhibitor
    
  • 5hvf, 5hvg, 5hvh – hCPB 2 (mutant) + nanobody inhibitor
    
  • 7nee, 7neu – hCPB 2 + inhibitor
    
  • 4p10 – hCPB 2 (mutant) + inhibitor
    
  • 3d67 – hCPB 2 + GEMSA
    
  • 1zli - hCPB + tick inhibitor
    
  • 1cpb, 3dgv – bCPB
    
  • 3d4u, 3osl – bCPB + CP inhibitor
    
  • 3glj – pCPB residues 16-416 - pig
    
  • 5jc6 – pCPB catalytic domain residues 111-416
    
  • 3wab, 3wc5, 3wc6, 3wc7, 5lyf, 5lyi, 5lyl, 4z65, 4uia, 2piy, 2piz, 2pj0, 2pj1, 2pj2, 2pj3, 2pj4, 2pj5, 2pj6, 2pj7, 2pj8, 2pj9, 2pja, 2pjb, 2pjc, 5j1q, 5zeq – pCPB catalytic domain + inhibitor
    
  • 5lyd, 4uib – pCPB catalytic domain (mutant) + inhibitor
    
  • 5lrg, 5lrj, 5lrk – pCPB catalytic domain + anabaenopepsin peptide
    
  • 2c1c – CPB – Corn earworm
    
• Procarboxypeptidase B
  • 1kwm - hPCPB
    
  • 1pba – pPCPB activation domain – NMR
    
  • 1nsa – pPCPB
    
  • 1z5r - pPCPB catalytic domain
    
  • 1pca – pPCPB + valine
    
  • 1zg7, 1zg8, 1zg9 – pPCPB + inhibitor
    
• Carboxypeptidase D
  • 5aq0 – hCPD transthyretin-like domain
    
  • 1qmu – dCPD domain II - duck
    
  • 1h8l - dCPD domain II + GEMSA
    
  • 3mn8 – DmCPD + GEMSA – Drosophila melanogaster
    
• Dipeptidyl carboxypeptidase I
  • 2iul, 2iux – hCPI (mutant)
    
  • 2c6f – hCPI N domain
    
  • 2x8y – DmCPI
    
  • 5l43 – AhCPI – Astrosporangium hypotensionis
    
• Dipeptidyl carboxypeptidase I complexes
  • 2oc2, 2xy9, 2xyd – hCPI + phosphate derivative
    
  • 3nxq - hCPI (mutant) + phosphate derivative
    
  • 3bkk, 3bkl, 3l3n – hCPI + inhibitor
    
  • 2ydm, 3zqz – hCPI + captopril derivative
    
  • 2x8z, 2x90, 2x91, 2x92, 2x93, 2x94, 2x95, 2x96, 2x97 – DmCPI + anti-hypersensitive drug
    
  • 2xhm - DmCPI + phosphate derivative
    
  • 5l44 – AhCPI + peptide inhibitor
    
• Carboxypeptidase L
  • 1ivy– hCPL
• Carboxypeptidase M
  • 1uwy – hCPM
• Carboxypeptidase N
  • 2nsm – hCPN catalytic domain
• Carboxypeptidase O
  • 5mrv – hCPO + metallo-CP inhibitor
    
• Carboxypeptidase S9
  • 8wt1 – CPS9 – Geobacillus stearothermophilus
    
• Carboxypeptidase T
  • 1obr, 3qnv – TvCPT – Thermoaclinomyces vulgaris
    
  • 3prt, 3v38, 4ihm, 8qvo – TvCPT (mutant)
    
  • 4djl, 6sn6, 6go2, 6t9y, 6tnk – TvCPT + sulfamoyl derivative
    
  • 4iav, 6f79, 6f75, 6f6q, 6z28 – TvCPT (mutant) + sulfamoyl derivative
    
  • 4duk – TvCPT + benzyl succinic acid
    
  • 4f8z – TvCPT + leucine derivative
    
  • 4ik2 – TvCPT (mutant) + leucine derivative
    
  • 4gm5 – TvCPT + arginine derivative
    
  • 3v7z – TvCPT + GEMSA
    
  • 7q87 – TvCPT + phenyllactic acid
    
• Carboxypeptidase Y
  • 1obr, 1wpx – yCPY + CPY inhibitor - yeast
• Serine carboxypeptidase
  • 3sc2 – wSCP II – wheat
    
  • 1ysc, 1cpy – ySCP
    
  • 2j7v – SeSCP – Synechococcus elongatus
    
  • 2j9o – SeSCP (mutant)
• Serine carboxypeptidase complexes
  • 1whs, 1wht - wSCP II + benzylsuccinate
    
  • 1bcr, 1bcs - wSCP II + antipain + arginine
    
  • 2j8y – SeSCP + penicillin
    
  • 2jbf - SeSCP (mutant) + penicillin
• Arginine carboxypeptidase
  • 3be7, 3dug – RCP
    
  • 3mtw – RCP + arginine derivative – Caulobacter vibrioides
• D-alanyl-D-alanine carboxypeptidase
  • 1w79, 1w8q – AACP – Actinomadura
    
  • 4rye – MtAACP
    
  • 5fsr – EcAACP
    
  • 5tr7 – AACP – Vibrio cholerae
    
  • 6osu – AACP – Francisella tularensis
    
  • 3pte, 1skf – StAACP – Streptomyces
    
  • 1es2, 1es3, 1es4, 1es5, 1esi, 1j9m – StAACP (mutant)
    
  • 1cef, 1ceg, 1hvb, 1pw1, 1pw8, 1pwc, 1pwd, 1pwg – StAACP + antibiotic
    
  • 1ikg, 1iki – StAACP + peptidoglycan fragment
    
  • 1mpl - StAACP + phosphonate inhibitor
    
  • 1scw, 1sde - StAACP + cyclic phosphate inhibitor
    
  • 1yqs - StAACP + sultam inhibitor
    
  • 1lbu – SaAACP + Zn – Streptomyces albus
    
  • 6c39 – AACP + Zn – Staphylococcus aureus
    
  • 5zhf – EfAACP + Zn – Enterococcus faecalis
    
  • 5hnm – EfAACP (mutant) + Zn
    
  • 6a6a – EfAACP + Zn + Ala
    
  • 5zhw – EfAACP + Zn + Ala-Ala
    
  • 2wke, 1w8y, 2vgj, 2vgk, 4ben - AcAACP + antibiotic
    
  • 2xdm, 2xk1, 2xln, 2y4a, 2y55, 2y59, 3zvt, 3zvw, 4b4x, 4b4z – AcAACP + boronic acid derivative
    
  • 3zcz – AcAACP + inhibitor
    
  • 5j8x – EcAACP + inhibitor
    
  • 6ntz – EcAACP + meropenem
    
• β-lactamase/D-alanine carboxypeptidase
  • 5evi - LACP – Pseudomonas syringae
    
  • 3ozh, 3rju – ACP – Yersinia pestis
    
• Glutamate carboxypeptidase II
  • 1z8l, 2oot – hECP II
    
  • 2c6c, 2jbj, 2jbk, 2or4, 3d7d, 3d7f, 3d7g, 3d7h, 3iww, 3sjf, 4jyw, 4jz0, 4lqg, 5ely, 5d29, 4x3r, 4w9y, 6hkz, 6hkj, 6h7z, 6h7y, 6f5l, 6ety, 6rbc, 6skh, 8bo8, 8bol, 8bow – hECP II + inhibitor
    
  • 6fe5, 6ez9, 5of0, 6s1x - hECP II (mutant) + inhibitor
    
  • 4p44, 4p45, 4p4e, 4p4d, 4p4f, 4p4i, 4p4j, 4p4b – hECP II + phosphoramidate inhibitor
    
  • 4ngm, 4ngn, 4ngp, 4ngq, 4ngr, 4ngs, 4ngt, 4oc0, 4oc1, 4oc2, 4oc3, 4oc4, 4oc5, 4ome, 5o5u, 5o5t, 5o5r - hECP II + urea derivative
    
  • 2c6g - hECP II + glutamate
    
  • 4mcr, 4mcs - hECP II (mutant) + glutamate
    
  • 4mcp, 4mcq, 5f09 - hECP II (mutant) + glutamate derivative
    
  • 3bhx, 3bi0, 3bi1 - hECP II + transition state analog
    
  • 2cij – hECP II + methionine
    
  • 2pvv - hECP II + serine-sulfate
    
  • 2c6p, 2pvw - hECP II + phosphate derivative
    
  • 3rbu – hECP II + PMPA
    
  • 6rti – hECP II + aptamer
    
  • 3bxm – hECP II (mutant) + dipeptide
    
  • 3sje, 3sjg, 3sjx - hECP II (mutant) + inhibitor
    
  • 2xef, 2xeg, 2xei, 2xej – hECP II + antibody-recruiting molecule
    
  • 1cg2 – ECP II – Pseudomonas
• Glutamate carboxypeptidase III
  • 3fec – hECP III
    
  • 3fed - hECP III + transition state analog
    
  • 3fee – hECP III + inhibitor
    
  • 3ff3 - hECP III + glutamate
• Prolyl carboxypeptidase
  • 3n2z - hPCP
• Tubulinyl-Tyr carboxypeptidase
  • 6j4u, 6j91, 6j9h, 6k81, 6lpg, 6ocf – hTTCP 1 + vasohibin-binding protein
    
  • 6j8n, 6nvq – hTTCP 1 (mutant) + vasohibin-binding protein
    
  • 6j7b – hTTCP 1 + vasohibin-binding protein + tubulinyl-Tyr derivative
    
  • 6j8f – hTTCP 1 + vasohibin-binding protein + tubulin peptide
    
  • 6j7b, 6ocg – hTTCP 1 + vasohibin-binding protein + Tyr derivative
    
  • 6och – hTTCP 1 + vasohibin-binding protein + parthenolide
    
  • 6wsl – hTTCP 1 + small vasohibin-binding protein + tubulin alpha-1A chain + tubulin beta-3 chain – Cryo EM
    
  • 6j4o, 6j4p, 6j4q, 6j4s, 6j4u, 6j8n, 6j91, 6qby – hTTCP 2 + vasohibin-binding protein
    
  • 6j4p – hTTCP 2 + small vasohibin-binding protein + Tyr derivative
    
  • 6j4v – hTTCP 2 + small vasohibin-binding protein + tubulin alpha-1B chain
    
  • 6j8o – hTTCP 2 + vasohibin-binding protein + peptide
    
  • 7zcw – hTTCP 2 + small vasohibin-binding protein + tubulin alpha-1B chain + tubulin beta-2B chain – Cryo EM
    
  • 6jzc, 6jze – mTTCP 2 + vasohibin-binding protein - mouse
    
  • 6jzd – mTTCP 2 + vasohibin-binding protein + peptide
    
• Angiotensin-converting enzyme-related carboxypeptidase
• See Angiotensin-Converting Enzyme
• M32 carboxypeptidase
  • 3hq2 – BsCP
• Muramoyl pentapeptide carboxypeptidase
  • 1lbu – SaCP
    
• Muramoyl tetrapeptide carboxypeptidase
  • 6uuk – CP – Oxalobacter formigenes
    
• Metallo-carboxypeptidase
  • 4a37 – PaCP – Pseudomonas aeruginosa
    
  • 4a38 – PaCP + benzyl succinic acid
    
  • 4a39 – PaCP + GEMSA
    

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