24ok: Difference between revisions
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==Crystal structure of human dUTPase complexed with Zinc.== | |||
<StructureSection load='24ok' size='340' side='right'caption='[[24ok]], [[Resolution|resolution]] 2.01Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[24ok]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=24OK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=24OK FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.01Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=24ok FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=24ok OCA], [https://pdbe.org/24ok PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=24ok RCSB], [https://www.ebi.ac.uk/pdbsum/24ok PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=24ok ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Squire | == Function == | ||
[[Category: Yosaatmadja | [https://www.uniprot.org/uniprot/DUT_HUMAN DUT_HUMAN] This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.<ref>PMID:8805593</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Krinkel BA]] | |||
[[Category: Loomes KM]] | |||
[[Category: Squire CJ]] | |||
[[Category: Yosaatmadja Y]] | |||
Latest revision as of 15:47, 1 April 2026
Crystal structure of human dUTPase complexed with Zinc.
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