9v7t: Difference between revisions
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The | ==PSI-LHCE supercomplex from Euglena gracilis.== | ||
<StructureSection load='9v7t' size='340' side='right'caption='[[9v7t]], [[Resolution|resolution]] 2.23Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9v7t]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Euglena_gracilis Euglena gracilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9V7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9V7T FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.23Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCR:BETA-CAROTENE'>BCR</scene>, <scene name='pdbligand=CLA:CHLOROPHYLL+A'>CLA</scene>, <scene name='pdbligand=DD6:(1~{R},3~{S},6~{S})-1,5,5-trimethyl-6-[(1~{Z},3~{E},5~{E},7~{E},9~{E},11~{E},13~{E},15~{E})-3,7,12,16-tetramethyl-18-[(4~{R})-2,6,6-trimethyl-4-oxidanyl-cyclohexen-1-yl]octadeca-1,3,5,7,9,11,13,15-octaen-17-ynyl]-7-oxabicyclo[4.1.0]heptan-3-ol'>DD6</scene>, <scene name='pdbligand=DGD:DIGALACTOSYL+DIACYL+GLYCEROL+(DGDG)'>DGD</scene>, <scene name='pdbligand=LHG:1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE'>LHG</scene>, <scene name='pdbligand=LMG:1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE'>LMG</scene>, <scene name='pdbligand=LMT:DODECYL-BETA-D-MALTOSIDE'>LMT</scene>, <scene name='pdbligand=PQN:PHYLLOQUINONE'>PQN</scene>, <scene name='pdbligand=SQD:1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL'>SQD</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9v7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9v7t OCA], [https://pdbe.org/9v7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9v7t RCSB], [https://www.ebi.ac.uk/pdbsum/9v7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9v7t ProSAT]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Euglena gracilis is a phototrophic flagellate that has evolved through secondary endosymbiotic events and belongs to green-lineage organisms. We report a unique structure of photosystem I-light harvesting complex I (PSI-LHCI) supercomplex from E. gracilis at a 2.23-angstrom resolution by cryo-electron microscopy. The supercomplex is composed of 8 core subunits and 16 LHCIs and exhibits distinctive structural features compared to its counterparts in green algae and plants. The LHCI subunits encircle the core complex, forming a two-layered arrangement that comprises six pairs of tightly packed heterodimers. Specifically, the 16 LHCIs consist of 4 diadinoxanthin-chlorophyll (Chl) a/b-binding antennae (Lhcbm) and 12 diadinoxanthin-Chl a-binding antennae (Lhca), and they exhibit characteristic pigment compositions combining features of green- and red-lineage organisms. These findings provide a robust structural foundation for elucidating the mechanisms of light harvesting and energy transfer as well as insights into the evolutionary changes of green-lineage PSI-LHCI. | |||
Structural basis of diadinoxanthin-Chl a/b-binding proteins in the photosystem I supercomplex of Euglena gracilis.,Bai T, Mao Z, Sun D, Tang Y, Lu Z, Ma F, Ma B, Chen J, Wang W, Li Y, Liu S, Yang Y, Wang Y, Tian L Sci Adv. 2026 Mar 6;12(10):eaea5561. doi: 10.1126/sciadv.aea5561. Epub 2026 Mar , 6. PMID:41790873<ref>PMID:41790873</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
[[Category: | <div class="pdbe-citations 9v7t" style="background-color:#fffaf0;"></div> | ||
[[Category: Mao | == References == | ||
[[Category: | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Euglena gracilis]] | |||
[[Category: Large Structures]] | |||
[[Category: Bai TY]] | |||
[[Category: Mao ZY]] | |||
[[Category: Tian LR]] | |||
Latest revision as of 16:02, 1 April 2026
PSI-LHCE supercomplex from Euglena gracilis.
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