9mzf: Difference between revisions

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'''Unreleased structure'''


The entry 9mzf is ON HOLD  until Paper Publication
==Cryo-EM structure of GLP-1R-Gs complex with peptide 15==
 
<StructureSection load='9mzf' size='340' side='right'caption='[[9mzf]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
Authors: Zhang, X., Belousoff, J.M., Wootten, D., Sexton, M.P.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9mzf]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens], [https://en.wikipedia.org/wiki/Lama_glama Lama glama] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9MZF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9MZF FirstGlance]. <br>
Description: Cryo-EM structure of GLP-1R-Gs complex with peptide 15
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr>
[[Category: Sexton, M.P]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9mzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9mzf OCA], [https://pdbe.org/9mzf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9mzf RCSB], [https://www.ebi.ac.uk/pdbsum/9mzf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9mzf ProSAT]</span></td></tr>
[[Category: Belousoff, J.M]]
</table>
[[Category: Wootten, D]]
== Function ==
[[Category: Zhang, X]]
[https://www.uniprot.org/uniprot/GBB1_HUMAN GBB1_HUMAN] Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.<ref>PMID:18611381</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Lama glama]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Belousoff JM]]
[[Category: Sexton MP]]
[[Category: Wootten D]]
[[Category: Zhang X]]

Latest revision as of 06:25, 22 April 2026

Cryo-EM structure of GLP-1R-Gs complex with peptide 15

9mzf, resolution 2.50Å

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