User:Davion Murray/Sandbox1: Difference between revisions
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==Introduction== | ==Introduction== | ||
Allosteric interaction of <scene name='11/1106429/Lon-lara_complex/1'>Caulobacter crescentus Lon N-terminus domain and regulatory protein (LarA)</scene>. Lon functions as an ATP depended (ATPase) AAA+ protease to degrade misfolded and denatured proteins to prevent proteoxic stress (1). Proteoxic stress caused by the accumulation of misfolded proteins can lead to cell death. AAA+ Proteases are found in all domains of life essential to maintaining the homeostasis of proteins within cells (2). For bacteria Lon is the protease that is responsible for the majority of protein homeostasis maintenance (2). | Allosteric interaction of <scene name='11/1106429/Lon-lara_complex/1'>Caulobacter crescentus Lon N-terminus domain and regulatory protein (LarA)</scene>. <scene name='11/1106429/Lon_protease/1'>Lon functions as an ATP depended (ATPase)</scene> AAA+ protease to degrade misfolded and denatured proteins to prevent proteoxic stress (1). Proteoxic stress caused by the accumulation of misfolded proteins can lead to cell death. AAA+ Proteases are found in all domains of life essential to maintaining the homeostasis of proteins within cells (2). For bacteria Lon is the protease that is responsible for the majority of protein homeostasis maintenance (2). | ||
==Structure== | ==Structure== | ||
