9t54: Difference between revisions
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==Coproheme decarboxylase H117A mutant from Listeria monocytogenes in complex with iron coproporphyrin III== | |||
<StructureSection load='9t54' size='340' side='right'caption='[[9t54]], [[Resolution|resolution]] 2.19Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9t54]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_EGD-e Listeria monocytogenes EGD-e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9T54 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9T54 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.194Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FEC:1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC+ACID+FERROUS+COMPLEX'>FEC</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9t54 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9t54 OCA], [https://pdbe.org/9t54 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9t54 RCSB], [https://www.ebi.ac.uk/pdbsum/9t54 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9t54 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CHDC_LISMO CHDC_LISMO] Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:27758026, PubMed:31423350). Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway (PubMed:27758026, PubMed:29536725, PubMed:31423350). The reaction occurs in a stepwise manner with a three-propionate intermediate (PubMed:27758026, PubMed:31423350).<ref>PMID:27758026</ref> <ref>PMID:29536725</ref> <ref>PMID:31423350</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Listeria monocytogenes EGD-e]] | |||
[[Category: Falb N]] | |||
[[Category: Hofbauer S]] | |||
Latest revision as of 03:45, 14 May 2026
Coproheme decarboxylase H117A mutant from Listeria monocytogenes in complex with iron coproporphyrin III
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